AP3M1 and AQP4

Data Source:
HPRD (in vitro)

		AP3M1	AQP4
Description		adaptor related protein complex 3 subunit mu 1	aquaporin 4
Image		No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Golgi Apparatus Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle Axon Cytoplasm	Extracellular Region Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Endosome Membrane Integral Component Of Membrane Basolateral Plasma Membrane Sarcolemma Astrocyte End-foot
	Molecular Function	Protein Binding Small GTPase Binding	Protein Binding Water Channel Activity
	Biological Process	Protein Targeting To Lysosome Endocytosis Anterograde Axonal Transport Viral Process Vesicle-mediated Transport Anterograde Synaptic Vesicle Transport	Renal Water Homeostasis Water Transport Cellular Water Homeostasis Water Homeostasis Multicellular Organismal Water Homeostasis Protein Homotetramerization Transmembrane Transport Cellular Response To Interferon-gamma Cerebrospinal Fluid Circulation
Pathways		Association of TriC/CCT with target proteins during biosynthesis	Vasopressin regulates renal water homeostasis via Aquaporins Passive transport by Aquaporins
Drugs
Diseases
GWAS		Cardiac troponin-I levels ( 31014085) Primary tooth development (number of teeth) ( 23704328) Primary tooth development (time to first tooth eruption) ( 23704328) Refractive error ( 32231278)	Blood urea nitrogen levels ( 31152163) Chronic kidney disease ( 31152163) Creatinine levels ( 29403010) Estimated glomerular filtration rate ( 31152163 30604766) Glomerular filtration rate ( 29403010) Metabolite levels ( 23823483)
Interacting Genes		15 interacting genes: AGTRAP AQP4 ARNT2 CRMP1 DVL3 IL36RN RSPH14 RUFY1 SIPA1L2 SLC12A4 SPAG16 TGOLN2 TRIM14 TRIM23 TRIM9	7 interacting genes: AP2M1 AP3M1 CREB3 CSNK2A1 CSNK2A2 GJA8 HPCAL4
Entrez ID		26985	361
HPRD ID		16496	02631
Ensembl ID		ENSG00000185009	ENSG00000171885
Uniprot IDs		A0A024QZR5 B4DRN6 Q9Y2T2	A0A5F9ZHR4 F1DSG4 P55087 V9PBN7
PDB IDs			3GD8
Enriched GO Terms of Interacting Partners?
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