SEC22A and TP53INP1

Data Source:
BioGRID (two hybrid)

		SEC22A	TP53INP1
Description		SEC22 homolog A, vesicle trafficking protein	tumor protein p53 inducible nuclear protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane	Nucleus Nucleoplasm Autophagosome Cytosol PML Body Cytoplasmic Vesicle
	Molecular Function	Transporter Activity Protein Binding	Protein Binding Antioxidant Activity
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport	Autophagosome Assembly Apoptotic Process Cell Cycle Arrest Negative Regulation Of Cell Population Proliferation Response To Heat Positive Regulation Of Autophagy Negative Regulation Of Gene Expression Negative Regulation Of Cell Migration Cellular Response To UV Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Transcription, DNA-templated Autophagic Cell Death Negative Regulation Of Fibroblast Proliferation Cellular Response To Ethanol Cellular Response To Hydroperoxide Cellular Response To Methyl Methanesulfonate Cellular Oxidant Detoxification Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Myofibroblast Differentiation
Pathways		COPII-mediated vesicle transport	TP53 Regulates Transcription of Genes Involved in Cytochrome C Release Regulation of TP53 Activity through Phosphorylation
Drugs
Diseases
GWAS		Gestational age at birth (maternal effect) ( 28877031)	Alzheimer's disease ( 31473137) Hemoglobin levels ( 32327693) Intraocular pressure ( 29617998) Macular thickness ( 30535121) Platelet distribution width ( 32888494) Serum uric acid levels ( 30993211 29403010) Type 2 diabetes ( 22885922 24509480 30054458 30297969 32499647 20581827 28869590) Urate levels ( 31578528)
Interacting Genes		106 interacting genes: ADGRG3 AQP6 ASGR2 ATP6AP2 BIK BNIP3 C10orf67 C16orf54 C16orf92 CALN1 CD207 CD300A CD7 CD74 CISD2 CLEC10A CLEC12B CLEC2D CLEC7A CREB3L1 CYB561 CYBRD1 DDIT4L DIABLO DTX2 EDA ELOVL4 ERLIN1 ERVFRD-1 FAM174A FAM209A FATE1 FUT3 GAD2 GGT6 GJB5 GJB6 GPR37L1 GRAMD2B HAVCR2 HCST HSD17B11 ICAM3 KCNJ2 LDLRAD1 LHFPL5 LMNA LPAR6 LRRC25 LSMEM2 MCOLN1 MFF MGST2 MINAR1 MS4A14 MS4A3 MS4A4A MSR1 OPRM1 PACC1 PEX12 PHB PTGES RASGRP4 RETREG3 RILPL1 RNASEK RNF144A RNF19B RNF5 SAR1A SCN3B SDHAF2 SFTPC SLC14A2 SLC30A2 SLC35C2 SLC39A2 SMIM3 SPAG4 STMN4 STOML3 STX1A STX2 STX4 SUSD3 SYNE4 TFR2 TLCD4 TMED9 TMEM106C TMEM159 TMEM174 TMEM237 TMEM45B TMEM52B TMEM71 TMEM79 TMIE TMPRSS2 TNFSF14 TP53INP1 TRAT1 TRIM59 TYRP1 ZFYVE27	11 interacting genes: GABARAP GABARAPL1 GABARAPL2 HIPK2 MAP1LC3A MAP1LC3C SEC22A SQSTM1 TP53 UNC119 YPEL3
Entrez ID		26984	94241
HPRD ID		15313	09367
Ensembl ID		ENSG00000121542	ENSG00000164938
Uniprot IDs		Q96IW7	A0A024R9C8 Q96A56
PDB IDs
Enriched GO Terms of Interacting Partners?
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