TP53INP1 and YPEL3

Data Source:
BioGRID (two hybrid)

		TP53INP1	YPEL3
Description		tumor protein p53 inducible nuclear protein 1	yippee like 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Autophagosome Cytosol PML Body Cytoplasmic Vesicle	Nucleolus
	Molecular Function	Protein Binding Antioxidant Activity	Metal Ion Binding
	Biological Process	Autophagosome Assembly Apoptotic Process Cell Cycle Arrest Negative Regulation Of Cell Population Proliferation Response To Heat Positive Regulation Of Autophagy Negative Regulation Of Gene Expression Negative Regulation Of Cell Migration Cellular Response To UV Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Transcription, DNA-templated Autophagic Cell Death Negative Regulation Of Fibroblast Proliferation Cellular Response To Ethanol Cellular Response To Hydroperoxide Cellular Response To Methyl Methanesulfonate Cellular Oxidant Detoxification Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Myofibroblast Differentiation	Positive Regulation Of Cellular Senescence
Pathways		TP53 Regulates Transcription of Genes Involved in Cytochrome C Release Regulation of TP53 Activity through Phosphorylation
Drugs
Diseases
GWAS		Alzheimer's disease ( 31473137) Hemoglobin levels ( 32327693) Intraocular pressure ( 29617998) Macular thickness ( 30535121) Platelet distribution width ( 32888494) Serum uric acid levels ( 30993211 29403010) Type 2 diabetes ( 22885922 24509480 30054458 30297969 32499647 20581827 28869590) Urate levels ( 31578528)	Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Schizophrenia ( 28991256 25056061 29483656)
Interacting Genes		11 interacting genes: GABARAP GABARAPL1 GABARAPL2 HIPK2 MAP1LC3A MAP1LC3C SEC22A SQSTM1 TP53 UNC119 YPEL3	121 interacting genes: APP ARMC7 ATG9A ATXN1L BCAS2 C10orf55 C19orf54 C1orf109 CABP2 CDCA4 CDKN2D COL8A1 CRYBA1 CRYBA2 CYB5R2 CYSRT1 DMRT3 DOK6 DOK7 EID2B FAM168B FANCL FGF21 FHL2 FHL3 FHL5 FNDC3B FRS3 GCA GCM2 GEM GUCD1 HDAC7 HEXIM2 HGS HNRNPH1 HOXA1 HR HSD3B7 HSPB2 HSPB2-C11orf52 INTS11 KLHL38 KRTAP13-2 KRTAP15-1 KRTAP23-1 KRTAP3-1 KRTAP3-3 KRTAP6-2 LARP4 LIMS3 LIMS4 LMO2 LONRF1 MAD2L2 MDFI MKRN3 MORN3 MYOZ1 MYOZ3 NRF1 NUFIP2 ODAM OSTF1 OTX1 PIK3R3 PITX1 PLSCR4 POLD1 POLR1C POU2AF1 PPP2CA PRKAA2 PRKAB2 PRR13 PRR20A PRR20B PRR20C PRR20D PRR20E PSMA3 QRICH1 RBPMS RFC5 SH2D4A SHC3 SMUG1 SPAG8 SPG21 SPRYD7 SRPK2 STK16 TASOR2 TBX6 TENT5A TENT5B TEPSIN TGM7 TLE5 TLX3 TOX2 TP53INP1 TRAPPC2L TRAPPC6A TRIM10 TRIM55 TRIM63 TRIM73 TRIP6 TSC1 TSSK3 UBTD2 VENTX VGLL3 VWC2L WWOX ZIC1 ZNF441 ZNF76 ZNF765 ZYX
Entrez ID		94241	83719
HPRD ID		09367	15683
Ensembl ID		ENSG00000164938	ENSG00000090238
Uniprot IDs		A0A024R9C8 Q96A56	A0A024R624 P61236
PDB IDs
Enriched GO Terms of Interacting Partners?
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