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SEC22A and CLEC7A
Data Source:
BioGRID
(two hybrid)
SEC22A
CLEC7A
Description
SEC22 homolog A, vesicle trafficking protein
C-type lectin domain containing 7A
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Endoplasmic Reticulum Membrane
Integral Component Of Membrane
Cytoplasm
Plasma Membrane
Cell Surface
Integral Component Of Membrane
Molecular Function
Transporter Activity
Protein Binding
(1->3)-beta-D-glucan Binding
Protein Binding
Carbohydrate Binding
Pattern Recognition Receptor Activity
MHC Protein Binding
Metal Ion Binding
Biological Process
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Protein Transport
Leukocyte Activation Involved In Immune Response
Positive Regulation Of Dendritic Cell Cytokine Production
Phagocytosis, Recognition
Inflammatory Response
Cell Recognition
Positive Regulation Of Cell Population Proliferation
Carbohydrate Mediated Signaling
Positive Regulation Of Gene Expression
Detection Of Fungus
Positive Regulation Of Cell Migration
Positive Regulation Of Protein-containing Complex Assembly
Detection Of Molecule Of Fungal Origin
Positive Regulation Of Interferon-gamma Production
Positive Regulation Of Interleukin-1 Beta Production
Positive Regulation Of Interleukin-10 Production
Positive Regulation Of Interleukin-12 Production
Positive Regulation Of Interleukin-2 Production
Positive Regulation Of Interleukin-6 Production
Positive Regulation Of Interleukin-8 Production
Positive Regulation Of Tumor Necrosis Factor Production
Positive Regulation Of Stress-activated MAPK Cascade
Positive Regulation Of Superoxide Anion Generation
T Cell Activation
Defense Response To Protozoan
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Innate Immune Response
Positive Regulation Of Nitric Oxide Biosynthetic Process
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Positive Regulation Of Phagocytosis
Positive Regulation Of Lymphocyte Activation
Positive Regulation Of Killing Of Cells Of Other Organism
Positive Regulation Of Respiratory Burst
Cellular Response To Molecule Of Fungal Origin
Positive Regulation Of Monocyte Chemotactic Protein-1 Production
Positive Regulation Of Wound Healing
Positive Regulation Of Cytokine Production Involved In Inflammatory Response
Positive Regulation Of Cell Maturation
Pathways
COPII-mediated vesicle transport
CLEC7A (Dectin-1) signaling
CLEC7A (Dectin-1) signaling
Drugs
Diseases
Chronic Mucocutaneous Candidiasis (CMC); Familial candidiasis (CANDF)
GWAS
Gestational age at birth (maternal effect) (
28877031
)
Interacting Genes
106 interacting genes:
ADGRG3
AQP6
ASGR2
ATP6AP2
BIK
BNIP3
C10orf67
C16orf54
C16orf92
CALN1
CD207
CD300A
CD7
CD74
CISD2
CLEC10A
CLEC12B
CLEC2D
CLEC7A
CREB3L1
CYB561
CYBRD1
DDIT4L
DIABLO
DTX2
EDA
ELOVL4
ERLIN1
ERVFRD-1
FAM174A
FAM209A
FATE1
FUT3
GAD2
GGT6
GJB5
GJB6
GPR37L1
GRAMD2B
HAVCR2
HCST
HSD17B11
ICAM3
KCNJ2
LDLRAD1
LHFPL5
LMNA
LPAR6
LRRC25
LSMEM2
MCOLN1
MFF
MGST2
MINAR1
MS4A14
MS4A3
MS4A4A
MSR1
OPRM1
PACC1
PEX12
PHB
PTGES
RASGRP4
RETREG3
RILPL1
RNASEK
RNF144A
RNF19B
RNF5
SAR1A
SCN3B
SDHAF2
SFTPC
SLC14A2
SLC30A2
SLC35C2
SLC39A2
SMIM3
SPAG4
STMN4
STOML3
STX1A
STX2
STX4
SUSD3
SYNE4
TFR2
TLCD4
TMED9
TMEM106C
TMEM159
TMEM174
TMEM237
TMEM45B
TMEM52B
TMEM71
TMEM79
TMIE
TMPRSS2
TNFSF14
TP53INP1
TRAT1
TRIM59
TYRP1
ZFYVE27
47 interacting genes:
ADAM33
AIP
ARL13B
ASGR2
BNIP3
BNIP3L
C14orf180
CALM3
CD53
CD74
CTXN3
CXCL9
FAM3A
FCGR1A
FNDC9
GJB1
HSPD1
IFNGR2
IL1RL1
JAGN1
KLRC1
KTN1
MTIF3
NEMP1
NINJ2
NSG2
OCLN
OLFM4
OPRM1
PTTG1IP
RANBP9
RHOU
SAR1A
SEC22A
SGCB
SMIM3
SPINT1
SUSD3
SYNE4
TEX29
TLCD4
TMEM79
TMPRSS2
TMPRSS4
UPK2
VSIR
ZFPL1
Entrez ID
26984
64581
HPRD ID
15313
08396
Ensembl ID
ENSG00000121542
ENSG00000172243
Uniprot IDs
Q96IW7
A0A024RAN9
A0A0S2Z5Q1
Q68D78
Q9BXN2
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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