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TP53INP1 and GABARAP
Data Source:
BioGRID
(two hybrid)
TP53INP1
GABARAP
Description
tumor protein p53 inducible nuclear protein 1
GABA type A receptor-associated protein
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Autophagosome
Cytosol
PML Body
Cytoplasmic Vesicle
Golgi Membrane
Autophagosome Membrane
Lysosome
Autophagosome
Smooth Endoplasmic Reticulum
Cytosol
Microtubule
Microtubule Associated Complex
Plasma Membrane
Axoneme
Actin Cytoskeleton
Cytoplasmic Vesicle
Cell Body
Synapse
Perinuclear Region Of Cytoplasm
Sperm Midpiece
Molecular Function
Protein Binding
Antioxidant Activity
Protein Binding
Microtubule Binding
Ubiquitin Protein Ligase Binding
Beta-tubulin Binding
GABA Receptor Binding
Biological Process
Autophagosome Assembly
Apoptotic Process
Cell Cycle Arrest
Negative Regulation Of Cell Population Proliferation
Response To Heat
Positive Regulation Of Autophagy
Negative Regulation Of Gene Expression
Negative Regulation Of Cell Migration
Cellular Response To UV
Regulation Of Apoptotic Process
Positive Regulation Of Apoptotic Process
Positive Regulation Of Transcription, DNA-templated
Autophagic Cell Death
Negative Regulation Of Fibroblast Proliferation
Cellular Response To Ethanol
Cellular Response To Hydroperoxide
Cellular Response To Methyl Methanesulfonate
Cellular Oxidant Detoxification
Regulation Of Signal Transduction By P53 Class Mediator
Negative Regulation Of Myofibroblast Differentiation
Autophagosome Assembly
Microtubule Cytoskeleton Organization
Autophagy Of Mitochondrion
Protein Targeting
Cellular Response To Nitrogen Starvation
Chemical Synaptic Transmission
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Macroautophagy
Autophagosome Maturation
Pathways
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release
Regulation of TP53 Activity through Phosphorylation
Macroautophagy
TBC/RABGAPs
Drugs
Diseases
GWAS
Alzheimer's disease (
31473137
)
Hemoglobin levels (
32327693
)
Intraocular pressure (
29617998
)
Macular thickness (
30535121
)
Platelet distribution width (
32888494
)
Serum uric acid levels (
30993211
29403010
)
Type 2 diabetes (
22885922
24509480
30054458
30297969
32499647
20581827
28869590
)
Urate levels (
31578528
)
Interacting Genes
11 interacting genes:
GABARAP
GABARAPL1
GABARAPL2
HIPK2
MAP1LC3A
MAP1LC3C
SEC22A
SQSTM1
TP53
UNC119
YPEL3
57 interacting genes:
AMBRA1
ANK2
ANK3
ATG101
ATG13
ATG3
ATG4A
ATG4B
ATG4C
ATG4D
ATG7
ATXN3
BIRC6
CUL3
DMPK
DVL2
FLCN
GABRG1
GABRG2
GABRG3
GPHN
HDAC5
KBTBD7
KDR
LMNB1
MAPK15
MEFV
MIB1
MLH1
MPC1
MYBPC2
NBR1
NEDD4
NSF
OPTN
PCM1
PGS1
PKP4
RB1CC1
SEC62
SNX18
SQSTM1
SRPK1
SRPK2
TAX1BP1
TBC1D25
TFRC
TLE5
TP53INP1
TRIM21
TRIM32
TSR2
TTN
TUBB3
ULK1
ULK2
VPS28
Entrez ID
94241
11337
HPRD ID
09367
05496
Ensembl ID
ENSG00000164938
ENSG00000170296
Uniprot IDs
A0A024R9C8
Q96A56
O95166
Q6IAW1
PDB IDs
1GNU
1KLV
1KM7
1KOT
3D32
3DOW
3WIM
4XC2
5DPS
6HB9
6HOG
6HOH
6HOJ
6HOK
6HYL
6HYM
6HYN
6HYO
7BRQ
7BRT
7BRU
7BV4
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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