GGT7 and GPR25

Data Source:
BioGRID (two hybrid, two hybrid)

		GGT7	GPR25
Description		gamma-glutamyltransferase 7	G protein-coupled receptor 25
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Peptidyltransferase Activity Protein Binding Glutathione Hydrolase Activity Hypoglycin A Gamma-glutamyl Transpeptidase Activity Leukotriene C4 Gamma-glutamyl Transferase Activity	G Protein-coupled Receptor Activity Protein Binding
	Biological Process	Translation Proteolysis Glutathione Biosynthetic Process Glutathione Catabolic Process Spermatogenesis Protein Phosphopantetheinylation Response To Estradiol Response To Lipopolysaccharide Response To Tumor Necrosis Factor Leukotriene D4 Biosynthetic Process Negative Regulation Of Response To Oxidative Stress	G Protein-coupled Receptor Signaling Pathway
Pathways		Glutathione synthesis and recycling Aflatoxin activation and detoxification	G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Coronary artery disease ( 29212778) Estimated glomerular filtration rate ( 31451708) Fish- and plant-related diet ( 32066663) Reticulocyte fraction of red cells ( 32888494) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Ankylosing spondylitis ( 23749187) Autoimmune thyroid disease ( 32581359) Refractive error ( 32231278)
Interacting Genes		13 interacting genes: CLDN19 CMTM7 CYB561 GPR25 HTR4 LHFPL5 LNPEP MALL MTNR1B SLC35A4 TLCD3A TMEM242 TSPO2	32 interacting genes: AQP6 ATP6V0C ATP6V0E1 BEST2 CNIH4 CREB3L1 CREB3L3 FATE1 GGT7 GJB1 IKBIP KASH5 LDLRAD1 LMNA MAP3K7 MFSD5 MMGT1 NAALADL2 PNMA1 RETN RHCG SHISAL1 SLC16A7 SLC35E3 SLCO4A1 STOM TMEM237 TMEM248 TMEM52B TPRA1 TSPAN12 VAPB
Entrez ID		2686	2848
HPRD ID		07488	03707
Ensembl ID		ENSG00000131067	ENSG00000170128
Uniprot IDs		A0PJJ9 Q9UJ14	O00155
PDB IDs
Enriched GO Terms of Interacting Partners?
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