GPR25 and CREB3L3

Data Source:
BioGRID (two hybrid)

		GPR25	CREB3L3
Description		G protein-coupled receptor 25	cAMP responsive element binding protein 3 like 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Golgi Membrane Chromatin Nucleus Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Membrane Integral Component Of Membrane
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding CAMP Response Element Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	G Protein-coupled Receptor Signaling Pathway	Positive Regulation Of Acute Inflammatory Response Regulation Of Transcription By RNA Polymerase II Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress
Pathways		G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production	CREB3 factors activate genes Assembly of active LPL and LIPC lipase complexes
Drugs
Diseases
GWAS		Ankylosing spondylitis ( 23749187) Autoimmune thyroid disease ( 32581359) Refractive error ( 32231278)	Apolipoprotein A1 levels ( 32203549) Triglyceride levels ( 32203549)
Interacting Genes		32 interacting genes: AQP6 ATP6V0C ATP6V0E1 BEST2 CNIH4 CREB3L1 CREB3L3 FATE1 GGT7 GJB1 IKBIP KASH5 LDLRAD1 LMNA MAP3K7 MFSD5 MMGT1 NAALADL2 PNMA1 RETN RHCG SHISAL1 SLC16A7 SLC35E3 SLCO4A1 STOM TMEM237 TMEM248 TMEM52B TPRA1 TSPAN12 VAPB	30 interacting genes: ATF6 BAD CEBPG CEP19 CREB3 CREB3L1 CSNK2A1 CYB561A3 DPY30 FATE1 GPR25 GSK3B KHDRBS1 KPNA2 MCRS1 MS4A13 PELI2 RHAG RIOK3 RUSF1 SGTA SGTB SLC38A7 SLC39A9 STX5 TCEANC TMEM239 TRAF3IP3 USP7 YIPF6
Entrez ID		2848	84699
HPRD ID		03707	16752
Ensembl ID		ENSG00000170128	ENSG00000060566
Uniprot IDs		O00155	Q68CJ9
PDB IDs
Enriched GO Terms of Interacting Partners?
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