GPR25 and RHCG

Data Source:
BioGRID (two hybrid)

		GPR25	RHCG
Description		G protein-coupled receptor 25	Rh family C glycoprotein
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane Apical Plasma Membrane Cytoplasmic Vesicle Extracellular Exosome
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding	Protein Binding Ammonium Transmembrane Transporter Activity Ankyrin Binding Identical Protein Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway	Cellular Ion Homeostasis Regulation Of PH Ammonium Transport Amine Transport Epithelial Cell Differentiation Homeostatic Process Transepithelial Ammonium Transport Ammonium Transmembrane Transport
Pathways		G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production	Rhesus glycoproteins mediate ammonium transport.
Drugs
Diseases
GWAS		Ankylosing spondylitis ( 23749187) Autoimmune thyroid disease ( 32581359) Refractive error ( 32231278)	Body size at age 10 ( 32376654) Dentures ( 31235808) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808)
Interacting Genes		32 interacting genes: AQP6 ATP6V0C ATP6V0E1 BEST2 CNIH4 CREB3L1 CREB3L3 FATE1 GGT7 GJB1 IKBIP KASH5 LDLRAD1 LMNA MAP3K7 MFSD5 MMGT1 NAALADL2 PNMA1 RETN RHCG SHISAL1 SLC16A7 SLC35E3 SLCO4A1 STOM TMEM237 TMEM248 TMEM52B TPRA1 TSPAN12 VAPB	14 interacting genes: C1QL4 C4orf3 CXCL9 EFNA5 ERMP1 FXYD6 GPR25 IGFBP5 MS4A13 TMEM60 TMEM97 TRARG1 UPK1B YIPF6
Entrez ID		2848	51458
HPRD ID		03707	16102
Ensembl ID		ENSG00000170128	ENSG00000140519
Uniprot IDs		O00155	Q9UBD6
PDB IDs			3HD6
Enriched GO Terms of Interacting Partners?
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