GPR25 and TPRA1

Data Source:
BioGRID (two hybrid)

		GPR25	TPRA1
Description		G protein-coupled receptor 25	transmembrane protein adipocyte associated 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Integral Component Of Membrane
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding	G Protein-coupled Receptor Activity Protein Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway	Lipid Metabolic Process G Protein-coupled Receptor Signaling Pathway Aging Embryonic Cleavage Negative Regulation Of Mitotic Cell Cycle Phase Transition
Pathways		G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs
Diseases
GWAS		Ankylosing spondylitis ( 23749187) Autoimmune thyroid disease ( 32581359) Refractive error ( 32231278)	Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) General risk tolerance (MTAG) ( 30643258) HDL cholesterol levels ( 32203549) Number of sexual partners ( 30643258) Refractive error ( 32231278) Risk-taking tendency (4-domain principal component model) ( 30643258) Triglyceride levels ( 32203549)
Interacting Genes		32 interacting genes: AQP6 ATP6V0C ATP6V0E1 BEST2 CNIH4 CREB3L1 CREB3L3 FATE1 GGT7 GJB1 IKBIP KASH5 LDLRAD1 LMNA MAP3K7 MFSD5 MMGT1 NAALADL2 PNMA1 RETN RHCG SHISAL1 SLC16A7 SLC35E3 SLCO4A1 STOM TMEM237 TMEM248 TMEM52B TPRA1 TSPAN12 VAPB	2 interacting genes: APP GPR25
Entrez ID		2848	131601
HPRD ID		03707	16318
Ensembl ID		ENSG00000170128	ENSG00000163870
Uniprot IDs		O00155	Q86W33
PDB IDs
Enriched GO Terms of Interacting Partners?
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