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FBXO2 and PFDN6
Data Source:
BioGRID
(two hybrid)
FBXO2
PFDN6
Description
F-box protein 2
prefoldin subunit 6
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Endoplasmic Reticulum
Cytosol
SCF Ubiquitin Ligase Complex
Organelle Membrane
Dendritic Spine
Cytoplasm
Prefoldin Complex
Molecular Function
Amyloid-beta Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Carbohydrate Binding
Ubiquitin Protein Ligase Activity
Amyloid-beta Binding
Protein Binding
Unfolded Protein Binding
Chaperone Binding
Biological Process
Protein Polyubiquitination
Cellular Protein Modification Process
Proteolysis
Glycoprotein Catabolic Process
Negative Regulation Of Cell Population Proliferation
Protein Ubiquitination
Ubiquitin-dependent ERAD Pathway
SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Regulation Of Protein Ubiquitination
Post-translational Protein Modification
Protein Folding
Chaperone-mediated Protein Complex Assembly
Negative Regulation Of Amyloid Fibril Formation
Pathways
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation
Prefoldin mediated transfer of substrate to CCT/TriC
Drugs
Diseases
GWAS
Autism spectrum disorder or schizophrenia (
28540026
)
Interacting Genes
16 interacting genes:
AHSG
BACE1
BRAP
ECPAS
IGH
ITGB1
PAX4
PFDN6
SKP1
STUB1
UBE2D1
UBE2D2
UBE2D3
UBE2E1
UBE2L3
VSTM1
12 interacting genes:
AIMP2
B4GALT2
CCHCR1
CEBPG
FBXO2
KANK2
KIFC3
MAGEB4
MBD3
PFDN5
RPRD1B
THAP11
Entrez ID
26232
10471
HPRD ID
06171
16135
Ensembl ID
ENSG00000116661
ENSG00000204220
Uniprot IDs
Q9UK22
O15212
Q5STK2
PDB IDs
6NR8
6NR9
6NRB
6NRC
6NRD
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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