PFDN6 and CEBPG

Data Source:
BioGRID (two hybrid)

		PFDN6	CEBPG
Description		prefoldin subunit 6	CCAAT enhancer binding protein gamma
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Prefoldin Complex	Chromatin Nucleus Nucleoplasm
	Molecular Function	Amyloid-beta Binding Protein Binding Unfolded Protein Binding Chaperone Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Transcription Factor Binding Identical Protein Binding Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding, Bending Protein-containing Complex Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Protein Folding Chaperone-mediated Protein Complex Assembly Negative Regulation Of Amyloid Fibril Formation	Liver Development Regulation Of Transcription By RNA Polymerase II Immune Response MRNA Metabolic Process B Cell Differentiation Positive Regulation Of Interferon-gamma Production Natural Killer Cell Mediated Cytotoxicity Enucleate Erythrocyte Differentiation Positive Regulation Of DNA Binding Negative Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of DNA Repair Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-binding Transcription Factor Activity
Pathways		Prefoldin mediated transfer of substrate to CCT/TriC	ATF4 activates genes in response to endoplasmic reticulum stress Response of EIF2AK4 (GCN2) to amino acid deficiency Response of EIF2AK1 (HRI) to heme deficiency
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026)	Inflammatory bowel disease ( 23128233) Schizophrenia ( 26198764)
Interacting Genes		12 interacting genes: AIMP2 B4GALT2 CCHCR1 CEBPG FBXO2 KANK2 KIFC3 MAGEB4 MBD3 PFDN5 RPRD1B THAP11	23 interacting genes: ATF2 ATF3 ATF4 ATF5 BATF BATF2 BATF3 CEBPA CEBPB CEBPD CEBPE CREB3 CREB3L3 DBP DDIT3 FOS FOSL1 GTF2F2 JUN MLLT6 PFDN6 PLAU POLR2M
Entrez ID		10471	1054
HPRD ID		16135	00738
Ensembl ID		ENSG00000204220	ENSG00000153879
Uniprot IDs		O15212 Q5STK2	P53567
PDB IDs		6NR8 6NR9 6NRB 6NRC 6NRD
Enriched GO Terms of Interacting Partners?
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