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GAS8 and IGFBP6
Data Source:
BioGRID
(two hybrid)
GAS8
IGFBP6
Description
growth arrest specific 8
insulin like growth factor binding protein 6
Image
No pdb structure
GO Annotations
Cellular Component
Golgi Apparatus
Cytosol
Microtubule
Plasma Membrane
Cilium
Axoneme
Motile Cilium
Ciliary Basal Body
Extracellular Region
Extracellular Space
Golgi Apparatus
Insulin-like Growth Factor Binary Complex
Molecular Function
Molecular_function
Protein Binding
Microtubule Binding
Fibronectin Binding
Signaling Receptor Binding
Protein Binding
Insulin-like Growth Factor I Binding
Insulin-like Growth Factor II Binding
Identical Protein Binding
Biological Process
Negative Regulation Of Cell Population Proliferation
Flagellated Sperm Motility
Cellular Protein Localization
Axoneme Assembly
Positive Regulation Of Smoothened Signaling Pathway
Cilium Movement Involved In Cell Motility
Positive Regulation Of Protein Localization To Cilium
Regulation Of Microtubule Binding
Activation Of MAPK Activity
Signal Transduction
Negative Regulation Of Cell Population Proliferation
Cell Migration
Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway
Cellular Protein Metabolic Process
Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways
Activation of SMO
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Drugs
Diseases
GWAS
Brain morphology (MOSTest) (
32665545
)
Disease progression in age-related macular degeneration (adjusted for baseline) (
29346644
)
Interacting Genes
111 interacting genes:
ARL6IP1
BCAR3
BHLHB9
BORCS6
BYSL
C1orf35
CARD10
CARD9
CBFA2T3
CCDC125
CCDC146
CCDC6
CCHCR1
CCNG1
CDC37
CDR2
CEP70
CFAP53
CINP
CKS1B
COG6
CPSF7
CRYBB1
CT45A1
CWF19L2
CYSRT1
DAXX
DDX17
DISC1
DMAP1
EAF1
EHHADH
EIF1AD
ERCC1
EVI5L
FAM161A
FAM161B
FHL2
GADD45GIP1
GCC1
GEM
GOLGA2
GRIPAP1
GSTA4
HEXIM2
HOMER3
HOMEZ
HOXA1
HSF2BP
IGFBP6
KDM1A
KRT14
KRT15
KRT16
KRT27
L3MBTL2
L3MBTL3
LASP1
LHX3
LMO1
LMO2
LZTS1
MAD1L1
MFAP1
MID2
MRFAP1L1
NDOR1
NKAPD1
PLK4
PNKP
PNMA5
POLR1C
POTEB3
PPFIA1
PRDM14
PRMT5
PRPF18
RALBP1
RBAK
RINT1
RUBCN
SCNM1
SKIL
SORBS3
SP7
SPATA18
SPG21
STAC3
TCEA2
THAP1
TNFAIP3
TRAF2
TRAF5
TRIM41
TRIM54
TSFM
TSGA10IP
TXLNA
TXLNB
USHBP1
YES1
YJU2
ZBTB22
ZBTB26
ZBTB39
ZNF212
ZNF250
ZNF572
ZNF620
ZNF629
ZNF792
37 interacting genes:
ALPP
ANKRD11
AQP1
C1orf74
CCDC116
CCDC28A
CDIPT
CREB5
EFEMP1
EFEMP2
ENKD1
EPDR1
GAS8
GET3
IGF1
IGF2
KRTAP10-8
KRTAP5-7
KRTAP5-9
MBD3
MEIS2
MSGN1
NCALD
PLEKHA7
POU4F2
RABGGTB
RANBP10
SDCBP
SGTA
SMCP
TF
UBAC1
UBQLN1
UBQLN2
UBQLN4
ZNF417
ZNF587
Entrez ID
2622
3489
HPRD ID
05533
00902
Ensembl ID
ENSG00000141013
ENSG00000167779
Uniprot IDs
A0A087WZT7
A0A384MR00
B7Z1U9
O95995
P24592
PDB IDs
1RMJ
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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