Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
IGFBP6 and ZNF587
Data Source:
BioGRID
(two hybrid)
IGFBP6
ZNF587
Description
insulin like growth factor binding protein 6
zinc finger protein 587
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Golgi Apparatus
Insulin-like Growth Factor Binary Complex
Nucleus
Molecular Function
Fibronectin Binding
Signaling Receptor Binding
Protein Binding
Insulin-like Growth Factor I Binding
Insulin-like Growth Factor II Binding
Identical Protein Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Protein Binding
Metal Ion Binding
Biological Process
Activation Of MAPK Activity
Signal Transduction
Negative Regulation Of Cell Population Proliferation
Cell Migration
Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway
Cellular Protein Metabolic Process
Negative Regulation Of Canonical Wnt Signaling Pathway
Regulation Of Transcription By RNA Polymerase II
Pathways
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Generic Transcription Pathway
Drugs
Diseases
GWAS
Disease progression in age-related macular degeneration (adjusted for baseline) (
29346644
)
Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes (
29221444
)
Interacting Genes
37 interacting genes:
ALPP
ANKRD11
AQP1
C1orf74
CCDC116
CCDC28A
CDIPT
CREB5
EFEMP1
EFEMP2
ENKD1
EPDR1
GAS8
GET3
IGF1
IGF2
KRTAP10-8
KRTAP5-7
KRTAP5-9
MBD3
MEIS2
MSGN1
NCALD
PLEKHA7
POU4F2
RABGGTB
RANBP10
SDCBP
SGTA
SMCP
TF
UBAC1
UBQLN1
UBQLN2
UBQLN4
ZNF417
ZNF587
130 interacting genes:
ADAMTSL4
AQP6
ASB15
ASB6
AXIN2
BEGAIN
C17orf50
CARD10
CARD9
CCDC125
CCDC136
CCDC85B
CEP44
CEP70
CHRDL2
CSRNP1
CYSRT1
DEF8
DHX57
EFEMP2
FCHSD2
FHL3
FHL5
FSD2
FST
GOLGA2
GOLGA6L9
GOPC
GSC2
HMBOX1
HOOK2
HOXA1
HSF2BP
IGFBP6
IKBKG
IKZF1
IKZF3
INSC
ISY1-RAB43
KATNBL1
KCTD7
KPRP
KRT31
KRT38
KRT40
KRTAP1-1
KRTAP1-3
KRTAP10-1
KRTAP10-10
KRTAP10-11
KRTAP10-3
KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP12-2
KRTAP12-3
KRTAP2-3
KRTAP2-4
KRTAP5-7
KRTAP5-9
LDOC1
LHX3
LIMS1
LMO3
LRP2BP
LZTS1
MCCD1
MDFI
MEOX2
MID2
MKRN3
MTUS2
MYF5
NBPF19
NDUFB7
NEK6
NKAPL
NOTCH2NLA
NR1D2
PBX2
PDE4DIP
PLSCR1
PNMA2
PPARA
PRDM14
PRICKLE4
PRPF31
RORB
RUNDC3A
SMAD9
SMYD5
SOX13
SPRED1
SPRY2
SPRY3
SSX2IP
STX11
TBC1D26
TCF4
TENM4
TFIP11
TMCC2
TNS2
TRAF1
TRIB3
TRIM23
TRIM27
TRIM36
TRIM37
TRIM41
TRIM54
TSC1
TSGA10
TXK
VPS52
VWC2
ZBTB43
ZBTB8A
ZGPAT
ZIM2
ZKSCAN8
ZNF286A
ZNF330
ZNF417
ZNF547
ZNF774
ZNF829
ZNF837
ZRANB1
Entrez ID
3489
84914
HPRD ID
00902
15864
Ensembl ID
ENSG00000167779
ENSG00000198466
Uniprot IDs
P24592
Q96SQ5
PDB IDs
1RMJ
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?