GAS8 and FAM161B

Data Source:
BioGRID (two hybrid)

		GAS8	FAM161B
Description		growth arrest specific 8	FAM161 centrosomal protein B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Cytosol Microtubule Plasma Membrane Cilium Axoneme Motile Cilium Ciliary Basal Body	Cytoplasmic Microtubule Cilium Microtubule Cytoskeleton
	Molecular Function	Molecular_function Protein Binding Microtubule Binding	Protein Binding
	Biological Process	Negative Regulation Of Cell Population Proliferation Flagellated Sperm Motility Cellular Protein Localization Axoneme Assembly Positive Regulation Of Smoothened Signaling Pathway Cilium Movement Involved In Cell Motility Positive Regulation Of Protein Localization To Cilium Regulation Of Microtubule Binding	Biological_process Cilium Organization
Pathways		Activation of SMO
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545)	Blood protein levels ( 28240269) Serum uric acid levels ( 29559957)
Interacting Genes		111 interacting genes: ARL6IP1 BCAR3 BHLHB9 BORCS6 BYSL C1orf35 CARD10 CARD9 CBFA2T3 CCDC125 CCDC146 CCDC6 CCHCR1 CCNG1 CDC37 CDR2 CEP70 CFAP53 CINP CKS1B COG6 CPSF7 CRYBB1 CT45A1 CWF19L2 CYSRT1 DAXX DDX17 DISC1 DMAP1 EAF1 EHHADH EIF1AD ERCC1 EVI5L FAM161A FAM161B FHL2 GADD45GIP1 GCC1 GEM GOLGA2 GRIPAP1 GSTA4 HEXIM2 HOMER3 HOMEZ HOXA1 HSF2BP IGFBP6 KDM1A KRT14 KRT15 KRT16 KRT27 L3MBTL2 L3MBTL3 LASP1 LHX3 LMO1 LMO2 LZTS1 MAD1L1 MFAP1 MID2 MRFAP1L1 NDOR1 NKAPD1 PLK4 PNKP PNMA5 POLR1C POTEB3 PPFIA1 PRDM14 PRMT5 PRPF18 RALBP1 RBAK RINT1 RUBCN SCNM1 SKIL SORBS3 SP7 SPATA18 SPG21 STAC3 TCEA2 THAP1 TNFAIP3 TRAF2 TRAF5 TRIM41 TRIM54 TSFM TSGA10IP TXLNA TXLNB USHBP1 YES1 YJU2 ZBTB22 ZBTB26 ZBTB39 ZNF212 ZNF250 ZNF572 ZNF620 ZNF629 ZNF792	70 interacting genes: ABI2 BICD2 BLOC1S2 BORCS6 CARD9 CBY1 CCDC125 CCDC13 CCDC136 CCDC138 CCDC172 CCDC57 CCDC83 CCDC88B CDR2L CEP55 CEP70 CINP CTNNA3 DDI1 EXOSC8 GAS8 GOLGA2 GOLGA6A GOLGA6L9 GPSM1 HAUS1 HOMER3 HOOK2 HSF2BP ISY1-RAB43 KIAA1328 LZTS1 MAPRE3 MDFI MEIS3 MID2 MIPOL1 MTUS2 NDUFB7 NECAB2 NR3C1 OIP5 PICK1 PLAGL2 PNMA1 PPP2R3C RINT1 SH3BP5L SMAD2 SPDEF SRGAP2B STX11 STX1B SYCE1 TEX11 TEX12 TFIP11 TRAF1 TRAF2 TRIM15 TSGA10 TSNAXIP1 TTC23 TTC23L USH1G USHBP1 VPS52 ZC4H2 ZRANB1
Entrez ID		2622	145483
HPRD ID		05533	12649
Ensembl ID		ENSG00000141013	ENSG00000156050
Uniprot IDs		A0A087WZT7 A0A384MR00 B7Z1U9 O95995	Q96MY7
PDB IDs
Enriched GO Terms of Interacting Partners?
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