GAS2 and TBC1D21

Data Source:
BioGRID (two hybrid)

		GAS2	TBC1D21
Description		growth arrest specific 2	TBC1 domain family member 21
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Microtubule Actin Filament Membrane	Acrosomal Vesicle Cytoskeleton Extracellular Exosome
	Molecular Function	Microtubule Binding Cytoskeletal Anchor Activity Actin Filament Binding	Actin Binding GTPase Activator Activity Protein Binding Small GTPase Binding
	Biological Process	Microtubule Cytoskeleton Organization Initiation Of Primordial Ovarian Follicle Growth Antral Ovarian Follicle Growth Apoptotic Process Cell Cycle Arrest Regulation Of Cell Shape Regulation Of Notch Signaling Pathway Ovulation Actin Crosslink Formation Basement Membrane Organization	Intracellular Protein Transport Spermatogenesis Cell Differentiation Activation Of GTPase Activity Regulation Of Cilium Assembly
Pathways		Caspase-mediated cleavage of cytoskeletal proteins
Drugs
Diseases
GWAS		Dialysis-related mortality ( 21546767) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Metabolite levels ( 23823483)	Coffee consumption (cups per day) ( 31837886) Estimated glomerular filtration rate ( 31152163) Exfoliation glaucoma or exfoliation syndrome ( 24938310) Feeling fed-up ( 29500382) Glucose homeostasis traits ( 25524916)
Interacting Genes		4 interacting genes: ACTA1 APP CAPN2 TBC1D21	29 interacting genes: APP CCDC158 CFAP53 EVI5L GAS2 GFAP GTF2E1 KIF26A KRT15 KRT35 KRT37 KRT38 KRT40 LCN2 MEOX2 NR1D2 NUTM1 PDCD2 PMF1 PMF1-BGLAP RAB3IP REL RIBC1 SAMD4A SEPTIN2 SNX7 STMN3 TCF12 TIMM10
Entrez ID		2620	161514
HPRD ID		04158	15473
Ensembl ID		ENSG00000148935	ENSG00000167139
Uniprot IDs		O43903	Q8IYX1
PDB IDs
Enriched GO Terms of Interacting Partners?
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