FXYD3 and SLC35A1

Data Source:
BioGRID (two hybrid)

		FXYD3	SLC35A1
Description		FXYD domain containing ion transport regulator 3	solute carrier family 35 member A1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome	Golgi Membrane Golgi Apparatus Integral Component Of Plasma Membrane Integral Component Of Membrane Integral Component Of Golgi Membrane
	Molecular Function	Chloride Channel Activity Sodium Channel Regulator Activity Ion Channel Regulator Activity	CMP-N-acetylneuraminate Transmembrane Transporter Activity UDP-galactose Transmembrane Transporter Activity Protein Binding Antiporter Activity
	Biological Process	Potassium Ion Transport Sodium Ion Transport Chloride Transport Ion Transmembrane Transport Chloride Transmembrane Transport Regulation Of Cardiac Conduction Regulation Of Sodium Ion Transmembrane Transporter Activity	Carbohydrate Metabolic Process Cellular Protein Modification Process Carbohydrate Transport CMP-N-acetylneuraminate Transmembrane Transport UDP-galactose Transmembrane Transport
Pathways		Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS	Sialic acid metabolism Defective SLC35A1 causes congenital disorder of glycosylation 2F (CDG2F) Defective SLC35A1 causes congenital disorder of glycosylation 2F (CDG2F) Transport of nucleotide sugars
Drugs
Diseases			Congenital disorders of glycosylation (CDG) type II
GWAS			Bone mineral density (hip) ( 30172743) Obesity-related traits ( 23251661)
Interacting Genes		64 interacting genes: AGR3 ANK1 AQP6 AQP9 BCL2L13 BEST2 CD79A CNR2 CREB3 CREB3L1 CYB5R3 EBP ERG28 ERGIC3 FAM209A FBXL12 FCGR2A FFAR2 GHITM GPR152 GPR37L1 GPR42 GPRC5D IBSP KASH5 KCNN4 LMNA LTC4S MAPK6 MFSD11 MFSD5 MGST1 MTIF3 NR4A1 NUDT3 PLPP6 SCN3B SERBP1 SGPL1 SLC10A1 SLC10A6 SLC16A12 SLC18A1 SLC1A1 SLC30A2 SLC35A1 SLC35B1 SLC35C2 SLC39A2 SPNS3 STRIT1 STX3 TIMM23 TIMMDC1 TLCD1 TMBIM6 TMEM179B TMEM50B TMEM52B TMEM80 TMEM86A TMEM97 TSPO2 XKR3	36 interacting genes: AQP6 ARL13B ASGR2 ASZ1 BCL2L13 CD53 CERS4 CPLX4 EBAG9 ERGIC3 F11R F2RL1 FAM209A FNDC9 FXYD3 GPX8 KIR3DL3 LHFPL5 LMNA MCFD2 MGST3 MRPS18B PIK3IP1 PLPP4 PSCA RELL2 SAR1A SDC3 SLC1A1 SLC34A2 SSMEM1 SYT2 TCTA TMEM139 TMPRSS2 TMX2
Entrez ID		5349	10559
HPRD ID		05410	09290
Ensembl ID		ENSG00000089356	ENSG00000164414
Uniprot IDs		Q14802	P78382
PDB IDs
Enriched GO Terms of Interacting Partners?
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