MAGI3 and DSCAML1

Data Source:
HPRD (two hybrid)

		MAGI3	DSCAML1
Description		membrane associated guanylate kinase, WW and PDZ domain containing 3	DS cell adhesion molecule like 1
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GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Cell-cell Junction Bicellular Tight Junction Membrane Cell Junction	Extracellular Space Plasma Membrane Cell Surface Integral Component Of Membrane Axon Synapse
	Molecular Function	Guanylate Kinase Activity Protein Binding ATP Binding Molecular Adaptor Activity	Protein Homodimerization Activity Cell-cell Adhesion Mediator Activity
	Biological Process	Apoptotic Process Signal Transduction Viral Process Intracellular Signal Transduction GMP Metabolic Process Regulation Of JNK Cascade GDP Metabolic Process	Cell Fate Determination Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Axonogenesis Axon Guidance Central Nervous System Development Brain Development Dorsal/ventral Pattern Formation Embryonic Skeletal System Morphogenesis Dendrite Self-avoidance
Pathways			DSCAM interactions
Drugs
Diseases
GWAS		Alopecia areata ( 25608926) Autoimmune thyroid disease ( 32581359) Bacteremia ( 27236921) Bulimia nervosa ( 23568457) Cerebrospinal fluid clusterin levels ( 26545630) Cognitive decline rate in late mild cognitive impairment ( 26252872) Crohn's disease ( 28067908) Gut microbiota (bacterial taxa) ( 27694959) Leukocyte telomere length ( 32109421) Neuroblastoma or malignant cutaneous melanoma ( 31605138) Obesity-related traits ( 23251661) Parental lifespan ( 30642433) Type 1 diabetes and autoimmune thyroid diseases ( 25936594)	Hippocampal volume in Alzheimer's disease dementia ( 29274321) Lipoprotein (a) - cholesterol levels ( 25575512) Menarche (age at onset) ( 23599027) Myopia ( 27182965) Putamen volume ( 29147026) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Triglyceride levels ( 28548082) Triglycerides ( 19074352 30275531) Very low density lipoprotein cholesterol levels ( 28548082)
Interacting Genes		16 interacting genes: ADGRB1 ADRB1 CRHR1 DSCAML1 FZD4 FZD7 GRIN2B LATS1 NRCAM PLXNB3 PTEN PTPRB RPS6KA1 TGFA TNK2 VANGL2	3 interacting genes: MAGI2 MAGI3 PLCL2
Entrez ID		260425	57453
HPRD ID		11290	10921
Ensembl ID		ENSG00000081026	ENSG00000177103
Uniprot IDs		Q5TCQ9	A0A384DVL8 Q8TD84
PDB IDs		3SOE	1VA9
Enriched GO Terms of Interacting Partners?
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