MAGI3 and NRCAM

Data Source:
HPRD (two hybrid)

		MAGI3	NRCAM
Description		membrane associated guanylate kinase, WW and PDZ domain containing 3	neuronal cell adhesion molecule
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GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Cell-cell Junction Bicellular Tight Junction Membrane Cell Junction	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Neuron Projection Axon Initial Segment
	Molecular Function	Guanylate Kinase Activity Protein Binding ATP Binding Molecular Adaptor Activity	Protein Binding Ankyrin Binding
	Biological Process	Apoptotic Process Signal Transduction Viral Process Intracellular Signal Transduction GMP Metabolic Process Regulation Of JNK Cascade GDP Metabolic Process	Angiogenesis Neuron Migration Axonogenesis Axon Guidance Axonal Fasciculation Synapse Assembly Central Nervous System Development Regulation Of Axon Extension Clustering Of Voltage-gated Sodium Channels Positive Regulation Of Neuron Differentiation Cell-cell Adhesion
Pathways			Interaction between L1 and Ankyrins NrCAM interactions Neurofascin interactions
Drugs
Diseases
GWAS		Alopecia areata ( 25608926) Autoimmune thyroid disease ( 32581359) Bacteremia ( 27236921) Bulimia nervosa ( 23568457) Cerebrospinal fluid clusterin levels ( 26545630) Cognitive decline rate in late mild cognitive impairment ( 26252872) Crohn's disease ( 28067908) Gut microbiota (bacterial taxa) ( 27694959) Leukocyte telomere length ( 32109421) Neuroblastoma or malignant cutaneous melanoma ( 31605138) Obesity-related traits ( 23251661) Parental lifespan ( 30642433) Type 1 diabetes and autoimmune thyroid diseases ( 25936594)	Blood protein levels ( 30072576) Coffee consumption ( 21876539) Diastolic blood pressure ( 27841878) Femoral neck bone geometry and menarche (age at onset) ( 23593202) Systolic blood pressure ( 27841878) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) White matter hyperintensities in ischemic stroke ( 26674333) White matter hyperintensity burden ( 25663218)
Interacting Genes		16 interacting genes: ADGRB1 ADRB1 CRHR1 DSCAML1 FZD4 FZD7 GRIN2B LATS1 NRCAM PLXNB3 PTEN PTPRB RPS6KA1 TGFA TNK2 VANGL2	8 interacting genes: ANK2 CNTN2 HSPA12A LNX1 MACF1 MAGI3 NFASC PTPRB
Entrez ID		260425	4897
HPRD ID		11290	07207
Ensembl ID		ENSG00000081026	ENSG00000091129
Uniprot IDs		Q5TCQ9	B7Z670 C9JYY6 Q14CA1 Q92823
PDB IDs		3SOE	1UEN 1UEY
Enriched GO Terms of Interacting Partners?
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