ZNF451 and RAP1GDS1

Data Source:
HPRD (two hybrid)

		ZNF451	RAP1GDS1
Description		zinc finger protein 451	Rap1 GTPase-GDP dissociation stimulator 1
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GO Annotations	Cellular Component	Nucleus PML Body	Mitochondrion Endoplasmic Reticulum Cytosol Extracellular Exosome
	Molecular Function	Transcription Corepressor Activity Protein Binding Metal Ion Binding SUMO Ligase Activity	GTPase Activator Activity Protein Binding
	Biological Process	Regulation Of Gene Expression Protein Sumoylation Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Histone H3-K9 Acetylation	Vascular Associated Smooth Muscle Contraction Myosin Filament Assembly Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Positive Regulation Of GTPase Activity Positive Regulation Of Mitochondrial Calcium Ion Concentration
Pathways
Drugs
Diseases
GWAS			Biochemical measures ( 19260141) Response to fenofibrate (total cholesterol levels) ( 27002377)
Interacting Genes		33 interacting genes: AR CALCOCO2 CDC5L CDCA4 CPTP CREB1 CREBBP FAM118A FXR2 HTT JMJD6 KDM1A KLHL40 LZTR1 MID2 OPLAH PCBD1 PIAS1 PIAS2 PIK3R3 PML PRMT1 PRMT8 PRPF40A RAP1GDS1 RNF40 SNIP1 SUMO1 SUMO2 SUV39H1 UBC UBE2I ZNF467	23 interacting genes: CDC42 DIRAS1 DIRAS2 DOC2A EGFR HRAS KIFAP3 KRAS MBIP NRAS PLEKHB1 PTPRF PUF60 RAB6B RAC1 RAP1A RAP2B RAP2C RHOA RNF19B RRAS RRAS2 ZNF451
Entrez ID		26036	5910
HPRD ID		10332	11763
Ensembl ID		ENSG00000112200	ENSG00000138698
Uniprot IDs		B4DYS2 Q96JY2 Q9Y4E5	B3KNU0 P52306 Q6U7G8
PDB IDs		5D2M	5XGC 5ZHX
Enriched GO Terms of Interacting Partners?
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