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RAP1GDS1 and RRAS
Data Source:
BioGRID
(two hybrid)
RAP1GDS1
RRAS
Description
Rap1 GTPase-GDP dissociation stimulator 1
RAS related
Image
GO Annotations
Cellular Component
Mitochondrion
Endoplasmic Reticulum
Cytosol
Extracellular Exosome
Plasma Membrane
Focal Adhesion
Extracellular Exosome
Molecular Function
GTPase Activator Activity
Protein Binding
GTPase Activity
Protein Binding
GTP Binding
GDP Binding
Protein-containing Complex Binding
Biological Process
Vascular Associated Smooth Muscle Contraction
Myosin Filament Assembly
Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration
Positive Regulation Of GTPase Activity
Positive Regulation Of Mitochondrial Calcium Ion Concentration
Leukocyte Differentiation
Ras Protein Signal Transduction
Positive Regulation Of Endothelial Cell Migration
Negative Regulation Of Cell Migration
Positive Regulation Of Angiogenesis
Regulation Of Protein Kinase B Signaling
Face Morphogenesis
Regulation Of ERK1 And ERK2 Cascade
Positive Regulation Of Endothelial Cell-matrix Adhesion Via Fibronectin
Positive Regulation Of Vasculogenesis
Pathways
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
Sema4D mediated inhibition of cell attachment and migration
Drugs
Diseases
GWAS
Biochemical measures (
19260141
)
Response to fenofibrate (total cholesterol levels) (
27002377
)
Estimated glomerular filtration rate (
31152163
)
Pulse pressure (
27618447
)
Schizophrenia (
25056061
29483656
)
Systolic blood pressure (
27618447
)
Interacting Genes
23 interacting genes:
CDC42
DIRAS1
DIRAS2
DOC2A
EGFR
HRAS
KIFAP3
KRAS
MBIP
NRAS
PLEKHB1
PTPRF
PUF60
RAB6B
RAC1
RAP1A
RAP2B
RAP2C
RHOA
RNF19B
RRAS
RRAS2
ZNF451
18 interacting genes:
ACY3
AFDN
ARAF
BCL2
EEF1A1
EPHB2
MRPL36
NAV2
NCK1
PPP2CA
RAF1
RALGDS
RAP1GDS1
RASIP1
RASSF5
SOS1
TRIM55
TRIM63
Entrez ID
5910
6237
HPRD ID
11763
01299
Ensembl ID
ENSG00000138698
ENSG00000126458
Uniprot IDs
B3KNU0
P52306
Q6U7G8
A0A024QZF2
P10301
PDB IDs
5XGC
5ZHX
2FN4
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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