GCA and LCP1

Data Source:
HPRD (in vitro, in vivo)

		GCA	LCP1
Description		grancalcin	lymphocyte cytosolic protein 1
Image
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Plasma Membrane Azurophil Granule Lumen Extracellular Exosome	Stress Fiber Ruffle Phagocytic Cup Podosome Extracellular Space Cytoplasm Cytosol Actin Filament Plasma Membrane Focal Adhesion Actin Cytoskeleton Cell Junction Filopodium Actin Filament Bundle Ruffle Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Calcium Ion Binding Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity	Actin Binding Integrin Binding Calcium Ion Binding Identical Protein Binding Actin Filament Binding GTPase Binding
	Biological Process	Neutrophil Degranulation Membrane Fusion	T Cell Activation Involved In Immune Response Protein Kinase A Signaling Cell Migration Extracellular Matrix Disassembly Cortical Actin Cytoskeleton Organization Animal Organ Regeneration Regulation Of Intracellular Protein Transport Interleukin-12-mediated Signaling Pathway Wound Healing, Spreading Of Cells Actin Filament Bundle Assembly Actin Filament Network Formation Actin Crosslink Formation Positive Regulation Of Podosome Assembly
Pathways		Neutrophil degranulation	Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs		Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Blood protein levels ( 30072576)	Blood protein levels ( 30072576 28240269) Lymphocyte counts ( 32888494) Mean platelet volume ( 32888494) Monocyte count ( 32888494) Non-alcoholic fatty liver disease histology (other) ( 23213074) Platelet count ( 32888494) Platelet distribution width ( 32888494) Systemic lupus erythematosus ( 26502338)
Interacting Genes		15 interacting genes: ABHD11 ATXN1 BPIFA1 C10orf55 C11orf49 CALCOCO2 GSTO2 LCP1 MAGEA8 PSMB4 RBFOX1 SRI TRAF1 TRAF2 YPEL3	5 interacting genes: AIF1 ATXN2 CNN3 GCA PRKACA
Entrez ID		25801	3936
HPRD ID		06122	01082
Ensembl ID		ENSG00000115271	ENSG00000136167
Uniprot IDs		B7Z322 H7BXD5 P28676	A0A024RDT4 P13796
PDB IDs		1F4O 1F4Q 1K94 1K95	2D85 5JOJ 5JOL
Enriched GO Terms of Interacting Partners?
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