GCA and RBFOX1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GCA	RBFOX1
Description		grancalcin	RNA binding fox-1 homolog 1
Image
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Plasma Membrane Azurophil Granule Lumen Extracellular Exosome	Nucleus Cytoplasm Trans-Golgi Network Cytoplasmic Stress Granule Nuclear Stress Granule
	Molecular Function	Calcium Ion Binding Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity	RNA Binding MRNA Binding Protein Binding Protein C-terminus Binding
	Biological Process	Neutrophil Degranulation Membrane Fusion	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Nervous System Development RNA Splicing RNA Transport
Pathways		Neutrophil degranulation	MECP2 regulates transcription factors
Drugs		Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Blood protein levels ( 30072576)	3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Adult body size ( 32376654) Adverse response to inhaled corticosteroid treatment x age interaction in asthma ( 32119686) Albumin-globulin ratio ( 29403010) Allergic rhinitis ( 25085501) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bitter alcoholic beverage consumption ( 31046077) Bitter non-alcoholic beverage consumption ( 31046077) Body mass index ( 28892062 25673413) Brain glucose metabolism (fluorodeoxyglucose uptake) ( 30596066) Brain volume in infants (cerebrospinal fluid) ( 28763065) Cerebellum white matter volume ( 31530798) Chronotype ( 30696823) Cocaine dependence ( 31212010) Cognitive decline rate in late mild cognitive impairment ( 26252872) Depression ( 29700475) Evening vs. morning chronotype (sMEQ score) ( 32579418) Extraversion ( 27918536) Feeling worry ( 29500382) General cognitive ability ( 29844566) General risk tolerance (MTAG) ( 30643258) Glaucoma ( 25027321) High myopia ( 31816047) Hydrolysed wheat protein allergy ( 31301374) Hyperopia ( 25233373) Insomnia symptoms (never/rarely vs. usually) ( 30804566) Intelligence (MTAG) ( 29326435) Intracranial aneurysm ( 29531279) Major depressive disorder ( 27479909 29728651) Mental health study participation (completed survey) ( 31263887) Metabolite levels ( 31628463) Myopia ( 27182965 25233373) Neurociticism ( 29500382) Neurofibrillary tangles ( 31497858) Neuroticism ( 29255261) Nickel levels ( 26025379) Obesity (extreme) ( 31852448) Obesity-related traits ( 23251661) Optic disc size ( 31809533) Photic sneeze reflex ( 27182965) Pit-and-Fissure caries ( 24556642) Refractive astigmatism ( 30306274) Refractive error ( 23396134 32231278 23474815) Renal cell carcinoma ( 31231134) Rheumatoid arthritis ( 30423114) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Systemising ( 31508503) Systolic blood pressure ( 30224653) Type 1 diabetes autoantibodies in high risk HLA genotype individuals (time to event) ( 29310926) Type 2 diabetes ( 30130595) Worry too long after an embarrassing experience ( 29500382)
Interacting Genes		15 interacting genes: ABHD11 ATXN1 BPIFA1 C10orf55 C11orf49 CALCOCO2 GSTO2 LCP1 MAGEA8 PSMB4 RBFOX1 SRI TRAF1 TRAF2 YPEL3	49 interacting genes: AGR2 ALG13 ARID5A ATN1 ATXN1 ATXN1L ATXN2 BHLHE40 C1orf94 CELF3 CRX DAB1 DAZAP2 DMRTB1 DVL2 FAM168A GCA HNRNPF HSFX1 HSFY1 HYPK KIFAP3 LASP1 LZTS2 MAGED1 NOC2L NUMBL P4HA3 PCBP4 POGZ PRR20A PRRC2A PSMF1 QKI RBFOX2 RBFOX3 RBM24 RBM47 RBPMS RBPMS2 RHOXF2 SIRPB1 SNRPN STRBP TEX37 TNIP1 TOLLIP UBL3 VENTX
Entrez ID		25801	54715
HPRD ID		06122	16091
Ensembl ID		ENSG00000115271	ENSG00000078328
Uniprot IDs		B7Z322 H7BXD5 P28676	A0A6Q8PH77 B7Z1U7 Q59HD3 Q9NWB1 X5D7T5 X5DNY3 X5DP44
PDB IDs		1F4O 1F4Q 1K94 1K95	2ERR 2N82 4ZKA
Enriched GO Terms of Interacting Partners?
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