LCP1 and CNN3

Data Source:
HPRD (in vivo)

		LCP1	CNN3
Description		lymphocyte cytosolic protein 1	calponin 3
Image			No pdb structure
GO Annotations	Cellular Component	Stress Fiber Ruffle Phagocytic Cup Podosome Extracellular Space Cytoplasm Cytosol Actin Filament Plasma Membrane Focal Adhesion Actin Cytoskeleton Cell Junction Filopodium Actin Filament Bundle Ruffle Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome	Cytosol Adherens Junction Focal Adhesion Postsynaptic Density Actin Cytoskeleton Neuronal Cell Body Dendritic Spine
	Molecular Function	Actin Binding Integrin Binding Calcium Ion Binding Identical Protein Binding Actin Filament Binding GTPase Binding	Actin Binding Calmodulin Binding Microtubule Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	T Cell Activation Involved In Immune Response Protein Kinase A Signaling Cell Migration Extracellular Matrix Disassembly Cortical Actin Cytoskeleton Organization Animal Organ Regeneration Regulation Of Intracellular Protein Transport Interleukin-12-mediated Signaling Pathway Wound Healing, Spreading Of Cells Actin Filament Bundle Assembly Actin Filament Network Formation Actin Crosslink Formation Positive Regulation Of Podosome Assembly	Epithelial Cell Differentiation Actomyosin Structure Organization Negative Regulation Of ATPase Activity Cell-cell Adhesion
Pathways		Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 28240269) Lymphocyte counts ( 32888494) Mean platelet volume ( 32888494) Monocyte count ( 32888494) Non-alcoholic fatty liver disease histology (other) ( 23213074) Platelet count ( 32888494) Platelet distribution width ( 32888494) Systemic lupus erythematosus ( 26502338)	Bipolar disorder ( 31043756) Palmitic acid (16:0) levels ( 23362303) Stearic acid (18:0) levels ( 23362303)
Interacting Genes		5 interacting genes: AIF1 ATXN2 CNN3 GCA PRKACA	4 interacting genes: F2RL1 FYN LCP1 VKORC1
Entrez ID		3936	1266
HPRD ID		01082	03848
Ensembl ID		ENSG00000136167	ENSG00000117519
Uniprot IDs		A0A024RDT4 P13796	Q15417
PDB IDs		2D85 5JOJ 5JOL
Enriched GO Terms of Interacting Partners?
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