LAPTM4B and NAALADL2

Data Source:
BioGRID (two hybrid)

		LAPTM4B	NAALADL2
Description		lysosomal protein transmembrane 4 beta	N-acetylated alpha-linked acidic dipeptidase like 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endosome Early Endosome Plasma Membrane Integral Component Of Membrane Late Endosome Membrane Multivesicular Body Membrane Cell Projection Multivesicular Body, Internal Vesicle	Nucleoplasm Integral Component Of Membrane
	Molecular Function	Protein Binding Kinase Binding Ubiquitin Protein Ligase Binding Ceramide Binding Phosphatidylinositol Bisphosphate Binding	Protein Binding
	Biological Process	Endosome Organization Endosome Transport Via Multivesicular Body Sorting Pathway Negative Regulation Of Transforming Growth Factor Beta1 Production Regulation Of Lysosomal Membrane Permeability Negative Regulation Of Lysosomal Protein Catabolic Process Regulation Of Lysosome Organization	Response To Bacterium
Pathways
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) QT interval ( 24952745)	3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Autism spectrum disorder ( 26398136) Beta blocker survival benefit in heart failure with reduced ejection fraction (time to all cause mortality x beta blocker interaction) ( 33012170) Deep ovarian and/or rectovaginal disease with dense adhesions ( 28333195) Familial lung adenocarcinoma ( 29924316) Height ( 23456168) Idiopathic downbeat nystagmus ( 32157568) Influenza A (H1N1) severity ( 26379185) Kawasaki disease ( 19132087) Loneliness ( 27629369) Metabolite levels (MHPG) ( 23319000) Mitochondrial DNA copy number ( 30704525) Number of sexual partners ( 30643258) Priapism in sickle cell disease ( 31668730) Prostate cancer aggressiveness ( 25939597) Rapid automised naming of pictures ( 30741946) Response to alcohol consumption (flushing response) ( 29460428) Sleep duration ( 23728906) Systemic lupus erythematosus ( 21408207)
Interacting Genes		21 interacting genes: BDKRB1 CGRRF1 CTXN3 CYB561A3 EMP1 GJA8 GPX8 IFNAR1 IGFBP5 ISLR2 MTIF3 NAALADL2 NRG1 ODF4 PIP5K1C SCARB2 SLC22A1 SLC22A2 SLC29A2 TMEM86B TRARG1	6 interacting genes: APP GPR25 GRM2 ITM2B LAPTM4B SLC30A3
Entrez ID		55353	254827
HPRD ID		13960	16388
Ensembl ID		ENSG00000104341	ENSG00000177694
Uniprot IDs		Q86VI4	Q58DX5
PDB IDs
Enriched GO Terms of Interacting Partners?
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