RNASEH1 and FAM3C

Data Source:
BioGRID (two hybrid)

		RNASEH1	FAM3C
Description		ribonuclease H1	FAM3 metabolism regulating signaling molecule C
Image
GO Annotations	Cellular Component	Cytoplasm	Extracellular Region Extracellular Space Golgi Apparatus Platelet Dense Granule Lumen Extracellular Exosome
	Molecular Function	Magnesium Ion Binding Nucleic Acid Binding RNA Binding RNA-DNA Hybrid Ribonuclease Activity Ribonuclease Activity Protein Binding	Cytokine Activity Protein Binding
	Biological Process	RNA Catabolic Process DNA Replication, Removal Of RNA Primer RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	Platelet Degranulation Signal Transduction Multicellular Organism Development Biological_process Negative Regulation Of Gluconeogenesis
Pathways			Platelet degranulation
Drugs
Diseases
GWAS			Biomedical quantitative traits ( 19396169) Bone mineral density (paediatric, lower limb) ( 24945404) Bone mineral density (paediatric, skull) ( 24945404) Bone mineral density (paediatric, total body less head) ( 24945404) Bone mineral density (paediatric, upper limb) ( 24945404) Calcaneus stiffness index ( 30779856) Forearm bone mineral density ( 26367794) Hand grip strength ( 27325353) Heel bone mineral density ( 30598549 28869591) Lung adenocarcinoma ( 28604730) Pediatric bone mineral content (radius) ( 26041818) Phenylephrine infusion rate during anesthesia ( 31455332) Total body bone mineral density ( 30172743) Ulna and radius bone mineral density ( 30172743)
Interacting Genes		8 interacting genes: ASPH EMD FAM3C NCS1 NRM TM9SF1 TMEM11 TRIM63	48 interacting genes: AHNAK2 BIK BNIP2 CLEC17A CLEC2D CLEC4E CREB3 CREB3L1 CXADR CYB5R3 ELOVL4 ERGIC3 EVI2B FAM209A FCGR1A FCGRT FFAR2 FKBP7 GGT6 GJB5 GPR42 GPX8 HHLA2 KCNA2 KIR2DL3 LMNA LRRC25 MFF PDZK1IP1 RELL2 RMDN3 RNASEH1 SAR1A SCN3B SLC10A6 SLC16A2 SLC18A1 SLC35C2 SPINT1 SSMEM1 STX1A TEX29 TMEM248 TMEM45B TMEM71 TMEM80 TMPRSS2 TMX2
Entrez ID		246243	10447
HPRD ID		04989	12270
Ensembl ID		ENSG00000171865	ENSG00000196937
Uniprot IDs		B3KUD4 E5KN15 O60930	Q92520
PDB IDs		2QK9 2QKB 2QKK 3BSU	5LC2
Enriched GO Terms of Interacting Partners?
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