FAM3C and FCGRT

Data Source:
BioGRID (two hybrid)

		FAM3C	FCGRT
Description		FAM3 metabolism regulating signaling molecule C	Fc fragment of IgG receptor and transporter
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Golgi Apparatus Platelet Dense Granule Lumen Extracellular Exosome	Extracellular Space External Side Of Plasma Membrane Endosome Membrane Integral Component Of Membrane
	Molecular Function	Cytokine Activity Protein Binding	Protein Binding IgG Binding Beta-2-microglobulin Binding Peptide Antigen Binding
	Biological Process	Platelet Degranulation Signal Transduction Multicellular Organism Development Biological_process Negative Regulation Of Gluconeogenesis	IgG Immunoglobulin Transcytosis In Epithelial Cells Mediated By FcRn Immunoglobulin Receptor Immune Response
Pathways		Platelet degranulation
Drugs
Diseases
GWAS		Biomedical quantitative traits ( 19396169) Bone mineral density (paediatric, lower limb) ( 24945404) Bone mineral density (paediatric, skull) ( 24945404) Bone mineral density (paediatric, total body less head) ( 24945404) Bone mineral density (paediatric, upper limb) ( 24945404) Calcaneus stiffness index ( 30779856) Forearm bone mineral density ( 26367794) Hand grip strength ( 27325353) Heel bone mineral density ( 30598549 28869591) Lung adenocarcinoma ( 28604730) Pediatric bone mineral content (radius) ( 26041818) Phenylephrine infusion rate during anesthesia ( 31455332) Total body bone mineral density ( 30172743) Ulna and radius bone mineral density ( 30172743)	Apolipoprotein B levels ( 32203549) Aspartate aminotransferase levels ( 29403010) Hematocrit ( 32888494) Hematological and biochemical traits ( 20139978) Hemoglobin ( 32888494) Plateletcrit ( 32888494) Red blood cell count ( 32888494) Reticulocyte count ( 32888494) Serum albumin level ( 23022100 29403010) Serum total protein level ( 23022100) Total cholesterol levels ( 29403010) Triglyceride levels ( 32203549)
Interacting Genes		48 interacting genes: AHNAK2 BIK BNIP2 CLEC17A CLEC2D CLEC4E CREB3 CREB3L1 CXADR CYB5R3 ELOVL4 ERGIC3 EVI2B FAM209A FCGR1A FCGRT FFAR2 FKBP7 GGT6 GJB5 GPR42 GPX8 HHLA2 KCNA2 KIR2DL3 LMNA LRRC25 MFF PDZK1IP1 RELL2 RMDN3 RNASEH1 SAR1A SCN3B SLC10A6 SLC16A2 SLC18A1 SLC35C2 SPINT1 SSMEM1 STX1A TEX29 TMEM248 TMEM45B TMEM71 TMEM80 TMPRSS2 TMX2	9 interacting genes: ALB B2M CA6 CLDN19 FAM3C MTDH NINJ2 PMP22 UPK2
Entrez ID		10447	2217
HPRD ID		12270	03257
Ensembl ID		ENSG00000196937	ENSG00000104870
Uniprot IDs		Q92520	A0A024QZI2 P55899
PDB IDs		5LC2	1EXU 3M17 3M1B 4K71 4N0F 4N0U 5BJT 5BXF 5WHK 6C97 6C98 6C99 6FGB 6ILM 6LA6 6LA7 6NHA 6QIO 6QIP 7C9V
Enriched GO Terms of Interacting Partners?
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