FAM3C and CLEC4E

Data Source:
BioGRID (two hybrid)

		FAM3C	CLEC4E
Description		FAM3 metabolism regulating signaling molecule C	C-type lectin domain family 4 member E
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Golgi Apparatus Platelet Dense Granule Lumen Extracellular Exosome	Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Cytokine Activity Protein Binding	Calcium Ion Binding Protein Binding Carbohydrate Binding Pattern Recognition Receptor Activity
	Biological Process	Platelet Degranulation Signal Transduction Multicellular Organism Development Biological_process Negative Regulation Of Gluconeogenesis	Pattern Recognition Receptor Signaling Pathway Stimulatory C-type Lectin Receptor Signaling Pathway Innate Immune Response
Pathways		Platelet degranulation	Dectin-2 family Dectin-2 family
Drugs			Cholesterol
Diseases
GWAS		Biomedical quantitative traits ( 19396169) Bone mineral density (paediatric, lower limb) ( 24945404) Bone mineral density (paediatric, skull) ( 24945404) Bone mineral density (paediatric, total body less head) ( 24945404) Bone mineral density (paediatric, upper limb) ( 24945404) Calcaneus stiffness index ( 30779856) Forearm bone mineral density ( 26367794) Hand grip strength ( 27325353) Heel bone mineral density ( 30598549 28869591) Lung adenocarcinoma ( 28604730) Pediatric bone mineral content (radius) ( 26041818) Phenylephrine infusion rate during anesthesia ( 31455332) Total body bone mineral density ( 30172743) Ulna and radius bone mineral density ( 30172743)	Takayasu arteritis ( 25604533)
Interacting Genes		48 interacting genes: AHNAK2 BIK BNIP2 CLEC17A CLEC2D CLEC4E CREB3 CREB3L1 CXADR CYB5R3 ELOVL4 ERGIC3 EVI2B FAM209A FCGR1A FCGRT FFAR2 FKBP7 GGT6 GJB5 GPR42 GPX8 HHLA2 KCNA2 KIR2DL3 LMNA LRRC25 MFF PDZK1IP1 RELL2 RMDN3 RNASEH1 SAR1A SCN3B SLC10A6 SLC16A2 SLC18A1 SLC35C2 SPINT1 SSMEM1 STX1A TEX29 TMEM248 TMEM45B TMEM71 TMEM80 TMPRSS2 TMX2	4 interacting genes: CXCL9 FAM3C FCER1G NKG7
Entrez ID		10447	26253
HPRD ID		12270	13075
Ensembl ID		ENSG00000196937	ENSG00000166523
Uniprot IDs		Q92520	F5H5X7 Q9ULY5
PDB IDs		5LC2	3WH2 3WH3
Enriched GO Terms of Interacting Partners?
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