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GABARAPL1 and SQSTM1
Data Source:
BioGRID
(affinity chromatography technology)
HPRD
(two hybrid)
GABARAPL1
SQSTM1
Description
GABA type A receptor associated protein like 1
sequestosome 1
Image
GO Annotations
Cellular Component
Autophagosome Membrane
Mitochondrion
Autophagosome
Endoplasmic Reticulum
Golgi Apparatus
Cytosol
Microtubule
Cytoplasmic Vesicle Membrane
Dendrite Membrane
Dendrite Cytoplasm
Cell Body
Phagophore Assembly Site
P-body
Nucleoplasm
Cytoplasm
Mitochondrion
Late Endosome
Autophagosome
Endoplasmic Reticulum
Cytosol
Inclusion Body
Aggresome
PML Body
Sarcomere
Intracellular Membrane-bounded Organelle
Amphisome
Autolysosome
Extracellular Exosome
Sperm Midpiece
Lewy Body
Molecular Function
Protein Binding
Tat Protein Binding
Ubiquitin Protein Ligase Binding
Beta-tubulin Binding
GABA Receptor Binding
Protein Serine/threonine Kinase Activity
Protein Kinase C Binding
Protein Binding
Zinc Ion Binding
Enzyme Binding
Protein Kinase Binding
Receptor Tyrosine Kinase Binding
Ubiquitin Protein Ligase Binding
Ionotropic Glutamate Receptor Binding
SH2 Domain Binding
Identical Protein Binding
Ubiquitin Binding
Protein-containing Complex Binding
K63-linked Polyubiquitin Modification-dependent Protein Binding
Biological Process
Autophagosome Assembly
Autophagy Of Mitochondrion
Cellular Response To Nitrogen Starvation
Macroautophagy
Autophagosome Maturation
Negative Regulation Of Transcription By RNA Polymerase II
Autophagy Of Mitochondrion
Mitophagy
Positive Regulation Of Protein Phosphorylation
Immune System Process
Response To Ischemia
Protein Phosphorylation
Ubiquitin-dependent Protein Catabolic Process
Autophagy
Apoptotic Process
Endosome Organization
Protein Localization
Regulation Of Mitochondrion Organization
Endosomal Transport
Macroautophagy
Cell Differentiation
Negative Regulation Of Protein Ubiquitination
Intracellular Signal Transduction
Aggrephagy
Positive Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Ras Protein Signal Transduction
Regulation Of Protein Complex Stability
Selective Autophagy
Interleukin-1-mediated Signaling Pathway
Response To Mitochondrial Depolarisation
Positive Regulation Of Long-term Synaptic Potentiation
Positive Regulation Of Protein Localization To Plasma Membrane
Protein Localization To Perinuclear Region Of Cytoplasm
Pathways
Macroautophagy
NRIF signals cell death from the nucleus
p75NTR recruits signalling complexes
NF-kB is activated and signals survival
PINK1-PRKN Mediated Mitophagy
Interleukin-1 signaling
Pexophagy
Drugs
Diseases
Paget's disease of bone and related disorders, including: ; Paget's disease of bone (PDB); Familial expansile osteolysis (FEO); Early-onset Paget's disease of bone (PDB2); Expansile skeletal hyperphosphatasia (ESH); Juvenile Paget's disease (JPD)
GWAS
Alzheimer's disease (late onset) (
24162737
)
Monocyte percentage of white cells (
32888494
)
Neutrophil percentage of white cells (
32888494
)
Interacting Genes
73 interacting genes:
AHNAK2
AMBRA1
ANK2
ATG13
ATG4A
ATG4B
ATG4D
BNIP3L
BSCL2
BSDC1
CALCOCO1
CALCOCO2
CREB3L2
CUL3
DISC1
DVL2
DYNLL1
ERBB2
ERBB3
FUNDC1
HSP90AA1
HSP90AB1
KBTBD7
KRTAP10-3
KRTAP10-7
KRTAP10-9
KXD1
MAPK15
MEFV
MLX
NEDD4
NFIA
OPRK1
OPTN
OSBPL3
PBXIP1
PSMB4
PTPRR
RABGAP1
RABGAP1L
RB1CC1
RCN2
RETREG3
SCYL3
SNCA
SQSTM1
SRPK1
SRPK2
STRN3
TAX1BP1
TBC1D1
TBC1D10A
TBC1D10B
TBC1D16
TBC1D17
TBC1D2
TBC1D25
TBC1D2B
TBC1D5
TBC1D7
TBC1D9
TBC1D9B
THAP7
TMEM131
TNIP1
TP53INP1
TRIM21
TRIM32
ULK1
UMAD1
VDR
WDFY3
ZBTB22
106 interacting genes:
ATXN3
BCL2
BMPR1B
BPTF
BRCA1
CALCR
CALM1
CALR
CAMK2A
CCNB1
CDC37
CDC6
CDK1
CRBN
CRYAB
CSNK1A1
CSNK2A1
DAXX
DAZAP2
DNAI1
DNAI2
DNAJC10
EEF1D
FKBP4
GABARAP
GABARAPL1
GABARAPL2
GABRR1
GABRR2
GEMIN4
GRB14
GRIA1
GRIA2
GRIA3
HSPA5
HSPB1
IKBKB
IRAK1
ISG15
KAT5
KCNAB2
KEAP1
LCK
LINC01554
LRRK2
MALT1
MAP1LC3A
MAP1LC3B
MAP2K5
MAPK13
MAPK14
MAPT
MBP
MEIS2
MLH1
MTDH
NBR1
NCOR1
NR2F2
NTRK1
NTRK2
NTRK3
PADI1
PAWR
PIK3CA
PIK3R1
PPHLN1
PRKCD
PRKCI
PRKCZ
RAD23A
RAD54L2
RELN
RIPK1
RNF166
RNF168
RPL37
SKP2
SMAD1
SMAD2
SMAD3
SMAD4
SMURF1
SNCA
STXBP1
TBK1
TGFBR1
TKT
TOE1
TP53INP1
TRAF6
TRIB3
TRIM21
TRIM55
TRIM63
TTN
UBA52
UBB
UBC
UBE2D2
UBE2D3
ULK2
VANGL2
WDR81
XIAP
YWHAZ
Entrez ID
23710
8878
HPRD ID
07601
03319
Ensembl ID
ENSG00000139112
ENSG00000161011
Uniprot IDs
A0A024RAP5
Q9H0R8
Q13501
PDB IDs
2L8J
2R2Q
5DPT
5LXH
5LXI
6HOI
6HOL
1Q02
2JY7
2JY8
2K0B
2KNV
4MJS
4UF8
4UF9
5YP7
5YP8
5YPA
5YPB
5YPC
5YPE
5YPF
5YPG
5YPH
6JM4
6KHZ
6MJ7
6TGY
6TH3
Enriched GO Terms of Interacting Partners
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