Description |
sequestosome 1 |
growth factor receptor bound protein 14 |
Image |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Alzheimer's disease (late onset) ( 24162737)
- Monocyte percentage of white cells ( 32888494)
- Neutrophil percentage of white cells ( 32888494)
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- Adventurousness ( 30643258)
- Blood pressure ( 24954895 21572416)
- Body fat percentage ( 26833246 31453325)
- Body fat percentage variance ( 31453325)
- Body mass index ( 29381148 26426971)
- Body mass index (age>50) ( 26426971)
- Body mass index x sex x age interaction (4df test) ( 26426971)
- Coronary artery disease ( 32469254 33020668)
- Diastolic blood pressure ( 28739976 27618452)
- Diastolic blood pressure (cigarette smoking interaction) ( 29455858)
- Diastolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
- Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
- Fasting blood insulin ( 25631608)
- Fasting blood insulin (BMI interaction) ( 22581228)
- Glomerular filtration rate in chronic kidney disease ( 26420894)
- Glycine levels ( 30837465)
- HDL cholesterol levels ( 30698716)
- HDL cholesterol levels in current drinkers ( 30698716)
- HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
- HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
- Hip circumference ( 25673412)
- Hip circumference adjusted for BMI ( 25673412)
- Hypertension ( 30487518)
- Immunoglobulin A vasculitis ( 28698626)
- LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
- Mean arterial pressure ( 29403010 30487518)
- Mean arterial pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
- Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962)
- Number of sexual partners ( 30643258)
- Perceived sweetness of sucrose ( 31005972)
- Pulse pressure ( 27841878 28739976 30487518)
- Pulse pressure x alcohol consumption interaction (2df test) ( 29912962)
- Response to statin therapy ( 20339536)
- Sexual dimorphism in anthropometric traits ( 23754948)
- Systolic blood pressure ( 26390057 28135244 27841878 29403010 28739976 27618447 27618452)
- Systolic blood pressure (cigarette smoking interaction) ( 29455858)
- Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
- Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
- Triglyceride levels ( 32203549 30698716)
- Triglyceride levels in current drinkers ( 30698716)
- Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
- Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
- Type 2 diabetes ( 22885922 24509480 21874001 30297969 29632382 32499647 30718926 28869590)
- Type 2 diabetes (adjusted for BMI) ( 29632382)
- Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
- Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500)
- Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
- Waist circumference adjusted for BMI in active individuals ( 28448500)
- Waist circumference adjusted for BMI in non-smokers ( 28443625)
- Waist circumference adjusted for body mass index ( 25673412 28448500)
- Waist-hip ratio ( 25673412 20935629)
- Waist-to-hip ratio adjusted for BMI ( 26426971)
- Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
- Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
- Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
- Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
- Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
- Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500)
- Waist-to-hip ratio adjusted for BMI in inactive individuals ( 28448500)
- Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625)
- Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
- Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)
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Interacting Genes |
106 interacting genes:
ATXN3
BCL2
BMPR1B
BPTF
BRCA1
CALCR
CALM1
CALR
CAMK2A
CCNB1
CDC37
CDC6
CDK1
CRBN
CRYAB
CSNK1A1
CSNK2A1
DAXX
DAZAP2
DNAI1
DNAI2
DNAJC10
EEF1D
FKBP4
GABARAP
GABARAPL1
GABARAPL2
GABRR1
GABRR2
GEMIN4
GRB14
GRIA1
GRIA2
GRIA3
HSPA5
HSPB1
IKBKB
IRAK1
ISG15
KAT5
KCNAB2
KEAP1
LCK
LINC01554
LRRK2
MALT1
MAP1LC3A
MAP1LC3B
MAP2K5
MAPK13
MAPK14
MAPT
MBP
MEIS2
MLH1
MTDH
NBR1
NCOR1
NR2F2
NTRK1
NTRK2
NTRK3
PADI1
PAWR
PIK3CA
PIK3R1
PPHLN1
PRKCD
PRKCI
PRKCZ
RAD23A
RAD54L2
RELN
RIPK1
RNF166
RNF168
RPL37
SKP2
SMAD1
SMAD2
SMAD3
SMAD4
SMURF1
SNCA
STXBP1
TBK1
TGFBR1
TKT
TOE1
TP53INP1
TRAF6
TRIB3
TRIM21
TRIM55
TRIM63
TTN
UBA52
UBB
UBC
UBE2D2
UBE2D3
ULK2
VANGL2
WDR81
XIAP
YWHAZ
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25 interacting genes:
CDC5L
CHFR
DAPK3
EGFR
ERBB2
FGFR1
FRS3
GIGYF1
GIGYF2
GOLGA2
HCK
IGF1R
INSR
IRS1
MAP3K14
MET
PDGFRA
PDGFRB
PRKCZ
SQSTM1
STK26
TEK
TNKS2
TRIM27
TRIM55
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Entrez ID |
8878 |
2888 |
HPRD ID |
03319 |
03313 |
Ensembl ID |
ENSG00000161011
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ENSG00000115290
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Uniprot IDs |
Q13501
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Q14449
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PDB IDs |
1Q02
2JY7
2JY8
2K0B
2KNV
4MJS
4UF8
4UF9
5YP7
5YP8
5YPA
5YPB
5YPC
5YPE
5YPF
5YPG
5YPH
6JM4
6KHZ
6MJ7
6TGY
6TH3
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2AUG
2AUH
4K81
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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