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GABARAPL1 and MLX
Data Source:
BioGRID
(two hybrid)
GABARAPL1
MLX
Description
GABA type A receptor associated protein like 1
MAX dimerization protein MLX
Image
No pdb structure
GO Annotations
Cellular Component
Autophagosome Membrane
Mitochondrion
Autophagosome
Endoplasmic Reticulum
Golgi Apparatus
Cytosol
Microtubule
Cytoplasmic Vesicle Membrane
Dendrite Membrane
Dendrite Cytoplasm
Cell Body
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Nuclear Membrane
Molecular Function
Protein Binding
Tat Protein Binding
Ubiquitin Protein Ligase Binding
Beta-tubulin Binding
GABA Receptor Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Transcription Factor Binding
Protein Homodimerization Activity
Protein Heterodimerization Activity
Sequence-specific Double-stranded DNA Binding
Biological Process
Autophagosome Assembly
Autophagy Of Mitochondrion
Cellular Response To Nitrogen Starvation
Macroautophagy
Autophagosome Maturation
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Macroautophagy
ChREBP activates metabolic gene expression
ChREBP activates metabolic gene expression
Drugs
Diseases
GWAS
Crohn's disease (
21102463
)
Type 2 diabetes (
30297969
29632382
30718926
)
Type 2 diabetes (time to event) (
32589924
)
Interacting Genes
73 interacting genes:
AHNAK2
AMBRA1
ANK2
ATG13
ATG4A
ATG4B
ATG4D
BNIP3L
BSCL2
BSDC1
CALCOCO1
CALCOCO2
CREB3L2
CUL3
DISC1
DVL2
DYNLL1
ERBB2
ERBB3
FUNDC1
HSP90AA1
HSP90AB1
KBTBD7
KRTAP10-3
KRTAP10-7
KRTAP10-9
KXD1
MAPK15
MEFV
MLX
NEDD4
NFIA
OPRK1
OPTN
OSBPL3
PBXIP1
PSMB4
PTPRR
RABGAP1
RABGAP1L
RB1CC1
RCN2
RETREG3
SCYL3
SNCA
SQSTM1
SRPK1
SRPK2
STRN3
TAX1BP1
TBC1D1
TBC1D10A
TBC1D10B
TBC1D16
TBC1D17
TBC1D2
TBC1D25
TBC1D2B
TBC1D5
TBC1D7
TBC1D9
TBC1D9B
THAP7
TMEM131
TNIP1
TP53INP1
TRIM21
TRIM32
ULK1
UMAD1
VDR
WDFY3
ZBTB22
31 interacting genes:
APP
BACH2
BEND7
CASK
CCT6A
DDIT4L
GABARAPL1
GABARAPL2
ID3
KRTAP13-3
LNX1
LNX2
MAD1L1
MEI4
MEOX1
MEOX2
MLXIP
MLXIPL
MNT
MXD1
MXD4
PIAS2
RBM39
RHBDD2
SAP30BP
TEPSIN
TLE5
TNNT2
UBE2I
ZBTB32
ZNF620
Entrez ID
23710
6945
HPRD ID
07601
04278
Ensembl ID
ENSG00000139112
ENSG00000108788
Uniprot IDs
A0A024RAP5
Q9H0R8
Q9UH92
PDB IDs
2L8J
2R2Q
5DPT
5LXH
5LXI
6HOI
6HOL
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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