MORC3 and SEC61B

Data Source:
BioGRID (affinity chromatography technology)

		MORC3	SEC61B
Description		MORC family CW-type zinc finger 3	SEC61 translocon subunit beta
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GO Annotations	Cellular Component	Nucleoplasm Nuclear Matrix PML Body	Endoplasmic Reticulum Sec61 Translocon Complex Endoplasmic Reticulum Membrane Cytosol Membrane Integral Component Of Membrane Endoplasmic Reticulum Sec Complex Endoplasmic Reticulum Quality Control Compartment
	Molecular Function	RNA Binding Protein Binding Zinc Ion Binding Methylated Histone Binding	RNA Binding Protein Binding Epidermal Growth Factor Binding
	Biological Process	Protein Phosphorylation Cell Aging Post-embryonic Development Viral Process Peptidyl-serine Phosphorylation Negative Regulation Of Fibroblast Proliferation Protein Stabilization Maintenance Of Protein Location In Nucleus	SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation Ubiquitin-dependent ERAD Pathway Retrograde Protein Transport, ER To Cytosol Posttranslational Protein Targeting To Membrane, Translocation Regulation Of Catalytic Activity
Pathways			ER-Phagosome pathway SRP-dependent cotranslational protein targeting to membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30224653) Height ( 31562340)	Adult body size ( 32376654) Asthma ( 31959851) Callous-unemotional behaviour ( 23874384) Gestational age at birth (maternal effect) ( 28877031) HDL cholesterol levels ( 32203549) Smoking status (ever vs never smokers) ( 30643258) Triglyceride levels ( 32203549)
Interacting Genes		5 interacting genes: ERCC6 KPNA2 RNF216 SUMO2 UBC	19 interacting genes: APOB ARL6 ATP13A2 AURKA BAG6 BMPR1A BUB1 CDKN2A FBXW7 GET3 GET4 MCC MLH3 MUTYH SEC63 SERP1 SPC25 TRAM1 UBL4A
Entrez ID		23515	10952
HPRD ID		10316	06715
Ensembl ID		ENSG00000159256	ENSG00000106803
Uniprot IDs		B4DHJ4 Q14149 Q4VBZ9	P60468
PDB IDs		4QQ4 5SVI 5SVX 5SVY 6O1E 6O5W	6W6L
Enriched GO Terms of Interacting Partners?
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