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SF3B3 and MIR19B1
Data Source:
BioGRID
(unspecified method)
SF3B3
MIR19B1
Description
splicing factor 3b subunit 3
microRNA 19b-1
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
U2 SnRNP
U12-type Spliceosomal Complex
Nucleolus
U2-type Precatalytic Spliceosome
Catalytic Step 2 Spliceosome
Extracellular Space
Perinuclear Region Of Cytoplasm
Blood Microparticle
Extracellular Vesicle
Molecular Function
Nucleic Acid Binding
Protein Binding
U2 SnRNA Binding
Protein-containing Complex Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Biological Process
RNA Splicing, Via Transesterification Reactions
MRNA Splicing, Via Spliceosome
RNA Splicing
Negative Regulation Of Protein Catabolic Process
Negative Regulation Of Inflammatory Response To Antigenic Stimulus
Positive Regulation Of Cell Population Proliferation
Negative Regulation Of Gene Expression
Negative Regulation Of Cardiac Muscle Cell Apoptotic Process
Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle
Negative Regulation Of Interleukin-6 Production
Gene Silencing By MiRNA
MiRNA Mediated Inhibition Of Translation
Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein
Cholesterol Homeostasis
Negative Regulation Of Coagulation
Positive Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of Cardiac Muscle Cell Proliferation
Positive Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development
Cellular Response To Bacterial Lipopeptide
Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Negative Regulation Of Cholesterol Efflux
Regulation Of Plasma Lipoprotein Particle Levels
Negative Regulation Of Serine-type Endopeptidase Activity
Regulation Of Canonical Wnt Signaling Pathway Involved In Cardiac Muscle Cell Fate Commitment
Negative Regulation Of Reverse Cholesterol Transport
Negative Regulation Of Matrix Metallopeptidase Secretion
Positive Regulation Of Apoptotic Process Involved In Development
Negative Regulation Of Apolipoprotein A-I-mediated Signaling Pathway
Pathways
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
Drugs
Quercetin
Diseases
GWAS
Brain morphology (MOSTest) (
32665545
)
Hippocampal volume in Alzheimer's disease dementia (
29274321
)
Malaria (
31844061
)
Interacting Genes
104 interacting genes:
APBB1
EFTUD2
EPS8
ERCC6
ERG
HCK
HGS
HSPB1
KLF10
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
MPP3
NAGK
NOL12
OSGEP
PHF5A
PPIL1
PRPF40A
RAD9A
RBM6
RUFY2
SF3B1
SF3B6
SMAD5
SNRNP200
SREK1
TAF9
TCERG1
TOE1
U2AF2
WBP4
WWOX
YWHAG
ZNF579
103 interacting genes:
AIMP1
AIMP2
APOBEC3B
AQR
C1QBP
CELF1
CELF2
CPSF1
CPSF2
CPSF3
CPSF4
CPSF6
CPSF7
CRTAP
CSTF3
DARS1
DDX1
DDX21
DDX3X
DHX36
DHX37
EIF2AK2
EPRS1
ERAL1
ESRP1
FAM98A
FIP1L1
FUS
G3BP2
HARS2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LARS1
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
MSI2
MYEF2
NOL6
NONO
NUDT21
P3H1
PATL1
PDCD11
PLOD1
PRMT1
PTBP1
PTBP3
PUF60
PUM1
PURA
QARS1
RARS1
RBBP6
RBFOX2
RBM12B
RBM14
RBM4
RBMS2
RTCB
SF3A1
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
SUGP2
SYMPK
SYNCRIP
TAF15
TRA2A
TRA2B
U2SURP
UPF1
UTP20
WDR33
WWP1
WWP2
YBX1
YBX2
YBX3
ZNF346
ZNF385A
Entrez ID
23450
406980
HPRD ID
12027
Ensembl ID
ENSG00000189091
ENSG00000284375
Uniprot IDs
A8K6V3
Q15393
PDB IDs
5IFE
5O9Z
5Z56
5Z57
5Z58
5ZYA
6AH0
6EN4
6FF4
6FF7
6QX9
6Y50
6Y5Q
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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