MIR19B1 and HNRNPK

Data Source:
BioGRID (unspecified method)

		MIR19B1	HNRNPK
Description		microRNA 19b-1	heterogeneous nuclear ribonucleoprotein K
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Perinuclear Region Of Cytoplasm Blood Microparticle Extracellular Vesicle	Chromatin Podosome Nucleus Nucleoplasm Cytoplasm Focal Adhesion Cytoplasmic Stress Granule Membrane Cell Projection Extracellular Exosome Catalytic Step 2 Spliceosome
	Molecular Function	MRNA Binding Involved In Posttranscriptional Gene Silencing	DNA Binding RNA Binding MRNA Binding Protein Binding Protein Domain Specific Binding Identical Protein Binding Cadherin Binding
	Biological Process	Negative Regulation Of Inflammatory Response To Antigenic Stimulus Positive Regulation Of Cell Population Proliferation Negative Regulation Of Gene Expression Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Interleukin-6 Production Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Cholesterol Homeostasis Negative Regulation Of Coagulation Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Cardiac Muscle Cell Proliferation Positive Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Cellular Response To Bacterial Lipopeptide Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Negative Regulation Of Cholesterol Efflux Regulation Of Plasma Lipoprotein Particle Levels Negative Regulation Of Serine-type Endopeptidase Activity Regulation Of Canonical Wnt Signaling Pathway Involved In Cardiac Muscle Cell Fate Commitment Negative Regulation Of Reverse Cholesterol Transport Negative Regulation Of Matrix Metallopeptidase Secretion Positive Regulation Of Apoptotic Process Involved In Development Negative Regulation Of Apolipoprotein A-I-mediated Signaling Pathway	MRNA Splicing, Via Spliceosome Regulation Of Transcription By RNA Polymerase II RNA Processing Signal Transduction Regulation Of Gene Expression Regulation Of Low-density Lipoprotein Particle Clearance Viral Process RNA Metabolic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Receptor-mediated Endocytosis Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of Low-density Lipoprotein Receptor Activity
Pathways			SUMOylation of RNA binding proteins mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA HCMV Late Events
Drugs			Artenimol Phenethyl Isothiocyanate
Diseases
GWAS			Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Platelet count ( 32888494) Plateletcrit ( 32888494) Triglyceride levels ( 32203549)
Interacting Genes		103 interacting genes: AIMP1 AIMP2 APOBEC3B AQR C1QBP CELF1 CELF2 CPSF1 CPSF2 CPSF3 CPSF4 CPSF6 CPSF7 CRTAP CSTF3 DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EIF2AK2 EPRS1 ERAL1 ESRP1 FAM98A FIP1L1 FUS G3BP2 HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 MYEF2 NOL6 NONO NUDT21 P3H1 PATL1 PDCD11 PLOD1 PRMT1 PTBP1 PTBP3 PUF60 PUM1 PURA QARS1 RARS1 RBBP6 RBFOX2 RBM12B RBM14 RBM4 RBMS2 RTCB SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B U2SURP UPF1 UTP20 WDR33 WWP1 WWP2 YBX1 YBX2 YBX3 ZNF346 ZNF385A	220 interacting genes: ABI1 ABI2 ADRB2 ANKRD28 APBB1 APOBEC1 APOBEC3C AQP5 AURKA BTRC C6orf223 C6orf226 CBLB CCAR1 CCDC187 CCDC33 CDKN1A CEBPB CIRBP CMTM5 CNNM3 CSK CTNNBL1 DALRD3 DDX1 DDX17 DDX5 DHX9 DIDO1 DOCK2 DUX4 EIF3F ELAVL1 ETNK2 FBXL18 FBXO7 FBXW7 FOXD4L1 FOXD4L3 FYN GFI1B GRAP2 GRB2 GZMA GZMK H3-4 HBZ HCK HMGB1 HNRNPA0 HNRNPL HNRNPLL IRGC ITK ITSN2 KCTD8 KHDRBS1 KHDRBS2 KHDRBS3 KLF1 LYN MAP2K2 MAPK10 MARK4 MATR3 MDM2 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I MISP MRPL9 MYPOP NCK2 NEDD4 NOTO NPDC1 PABPC1 PCBP1 PCBP2 PCDHB14 PCGF3 PELI2 PGAP6 PIN1 PPP1R10 PRKCD PRMT1 PRPF31 PRPF40A PRR3 QKI RALY RAMAC RASAL3 RASD1 RBFOX2 RBM10 RBM14 RBM3 RBM4 RBM41 RBM42 RBM7 RBMX RBMY1A1 RBMY1F RBMY1J RBPMS2 RNA18SN5 RNA28SN5 RNF4 RPH3AL RTP5 SAFB SF1 SMAD3 SNRPA SORBS3 SPG7 SRC SREK1 SRPK2 SRRT SRSF3 SUMO1 SUMO2 SYNCRIP TBP TCERG1 TCF23 TERF2IP TH TLE5 TYK2 U2AF1 U2AF1L5 UBE2I VAV1 WBP4 WWOX YBX1 YTHDC1 YWHAQ ZFC3H1 ZNF385C ZNF408 ZNF526 ZNF575 ZNF688 ZNF792 ZNRF2P1
Entrez ID		406980	3190
HPRD ID			02834
Ensembl ID		ENSG00000284375	ENSG00000165119
Uniprot IDs			B4DUQ1 P61978
PDB IDs			1J5K 1KHM 1ZZI 1ZZJ 1ZZK
Enriched GO Terms of Interacting Partners?
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