SF3B3 and SF3B6

Data Source:
BioGRID (pull down)

		SF3B3	SF3B6
Description		splicing factor 3b subunit 3	splicing factor 3b subunit 6
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm U2 SnRNP U12-type Spliceosomal Complex Nucleolus U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm U2-type Spliceosomal Complex U2 SnRNP U12-type Spliceosomal Complex Precatalytic Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	Nucleic Acid Binding Protein Binding U2 SnRNA Binding Protein-containing Complex Binding	RNA Binding MRNA Binding Protein Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Splicing Negative Regulation Of Protein Catabolic Process	MRNA Splicing, Via Spliceosome Blastocyst Formation
Pathways		mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway	mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs		Quercetin
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Malaria ( 31844061)
Interacting Genes		104 interacting genes: APBB1 EFTUD2 EPS8 ERCC6 ERG HCK HGS HSPB1 KLF10 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I MPP3 NAGK NOL12 OSGEP PHF5A PPIL1 PRPF40A RAD9A RBM6 RUFY2 SF3B1 SF3B6 SMAD5 SNRNP200 SREK1 TAF9 TCERG1 TOE1 U2AF2 WBP4 WWOX YWHAG ZNF579	7 interacting genes: APP ERBB3 PHF5A SF3B1 SF3B3 SF3B5 U2AF2
Entrez ID		23450	51639
HPRD ID		12027	09702
Ensembl ID		ENSG00000189091	ENSG00000115128
Uniprot IDs		A8K6V3 Q15393	Q9Y3B4
PDB IDs		5IFE 5O9Z 5Z56 5Z57 5Z58 5ZYA 6AH0 6EN4 6FF4 6FF7 6QX9 6Y50 6Y5Q	2F9D 2F9J 2FHO 3LQV 5Z56 5Z57 5Z58 6AH0 6FF4 6FF7 6Y53 6Y5Q
Enriched GO Terms of Interacting Partners?
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