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GRIP1 and IRF3
Data Source:
HPRD
(two hybrid, in vitro)
GRIP1
IRF3
Description
glutamate receptor interacting protein 1
interferon regulatory factor 3
Image
GO Annotations
Cellular Component
Endoplasmic Reticulum Membrane
Cytosol
Plasma Membrane
Postsynaptic Density
Dendrite
Cytoplasmic Vesicle
Neuron Projection
Perikaryon
Membrane Raft
Postsynaptic Membrane
Glutamatergic Synapse
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrion
Cytosol
Molecular Function
Protein Binding
Beta-catenin Binding
Protein C-terminus Binding
Signaling Receptor Complex Adaptor Activity
Glucocorticoid Receptor Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
Protein Binding
Protein Domain Specific Binding
Identical Protein Binding
Protein Homodimerization Activity
Sequence-specific DNA Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Dendrite Development
Intracellular Signal Transduction
Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane
Vesicle-mediated Transport In Synapse
Positive Regulation Of Neuron Projection Arborization
Negative Regulation Of Transcription By RNA Polymerase II
Immune System Process
Regulation Of Transcription By RNA Polymerase II
Apoptotic Process
Cellular Response To DNA Damage Stimulus
Viral Process
Lipopolysaccharide-mediated Signaling Pathway
Regulation Of Type I Interferon Production
Negative Regulation Of Type I Interferon Production
Positive Regulation Of Type I Interferon Production
Positive Regulation Of Interferon-alpha Production
Positive Regulation Of Interferon-beta Production
TRIF-dependent Toll-like Receptor Signaling Pathway
MDA-5 Signaling Pathway
Regulation Of Apoptotic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Inflammatory Response
Defense Response To Virus
Interferon-gamma-mediated Signaling Pathway
Type I Interferon Signaling Pathway
Positive Regulation Of Type I Interferon-mediated Signaling Pathway
Cellular Response To Exogenous DsRNA
Macrophage Apoptotic Process
Programmed Necrotic Cell Death
Cellular Response To Virus
Pathways
Trafficking of GluR2-containing AMPA receptors
ISG15 antiviral mechanism
IRF3 mediated activation of type 1 IFN
IRF3 mediated activation of type 1 IFN
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production
Regulation of innate immune responses to cytosolic DNA
IRF3-mediated induction of type I IFN
Interferon gamma signaling
TICAM1-dependent activation of IRF3/IRF7
Interferon alpha/beta signaling
TRAF3-dependent IRF activation pathway
TRAF6 mediated IRF7 activation
Negative regulators of DDX58/IFIH1 signaling
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
Drugs
Diseases
GWAS
Basophil percentage of granulocytes (
27863252
)
Basophil percentage of white cells (
27863252
)
Post bronchodilator FEV1/FVC ratio (
26634245
)
Autoimmune thyroid disease (
32581359
)
Schizophrenia (
29483656
)
Vitiligo (
27723757
)
Interacting Genes
42 interacting genes:
AGAP2
AR
CARM1
CSPG4
DEPDC1B
DZIP3
EEPD1
EFNA5
EFNB1
EFNB2
EP300
ESR1
FGF12
FLII
GPR37
GRIA1
GRIA3
GRIA4
GRIK1
GRIK2
GRIPAP1
GRM2
GRM3
GRM7
H3C1
HUS1
IRF3
MFAP3
NCOA6
NEK6
NR3C1
NUMBL
PICK1
PPARG
PRKD2
PRMT1
RXRA
THRA
UBE2I
VDR
WDR6
XDH
30 interacting genes:
CREBBP
EP300
EWSR1
FBXO7
GRIP1
HERC5
HSP90AA1
IKBKE
IRF5
IRF7
MAPK8
MAVS
PEX19
PIAS4
PPIB
PRDX1
RB1
RBL1
RELA
SERPINB2
SGTA
SMURF2
SYT1
TBK1
TICAM1
TICAM2
TOMM70
TRIM26
TRIM55
TRIM63
Entrez ID
23426
3661
HPRD ID
19086
04769
Ensembl ID
ENSG00000155974
ENSG00000126456
Uniprot IDs
Q9Y3R0
E2GIM5
E2GIM6
E2GIM7
E2GIM8
E2GIM9
M0QYT9
Q14653
PDB IDs
2JIL
1J2F
1QWT
1T2K
1ZOQ
2O61
2O6G
2PI0
3A77
3QU6
5JEJ
5JEK
5JEL
5JEM
5JEO
5JER
6SIV
6SJA
7JFL
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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