GRIP1 and WDR6

Data Source:
BioGRID (two hybrid)

		GRIP1	WDR6
Description		glutamate receptor interacting protein 1	WD repeat domain 6
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Postsynaptic Density Dendrite Cytoplasmic Vesicle Neuron Projection Perikaryon Membrane Raft Postsynaptic Membrane Glutamatergic Synapse	Cytoplasm Cytosol Plasma Membrane COP9 Signalosome
	Molecular Function	Protein Binding Beta-catenin Binding Protein C-terminus Binding Signaling Receptor Complex Adaptor Activity Glucocorticoid Receptor Binding	RNA Binding Protein Binding
	Biological Process	Dendrite Development Intracellular Signal Transduction Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Vesicle-mediated Transport In Synapse Positive Regulation Of Neuron Projection Arborization	Cell Cycle Arrest Negative Regulation Of Cell Population Proliferation Negative Regulation Of Autophagy
Pathways		Trafficking of GluR2-containing AMPA receptors
Drugs
Diseases
GWAS		Basophil percentage of granulocytes ( 27863252) Basophil percentage of white cells ( 27863252) Post bronchodilator FEV1/FVC ratio ( 26634245)	Blood protein levels ( 28240269) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Menarche (age at onset) ( 25231870) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)
Interacting Genes		42 interacting genes: AGAP2 AR CARM1 CSPG4 DEPDC1B DZIP3 EEPD1 EFNA5 EFNB1 EFNB2 EP300 ESR1 FGF12 FLII GPR37 GRIA1 GRIA3 GRIA4 GRIK1 GRIK2 GRIPAP1 GRM2 GRM3 GRM7 H3C1 HUS1 IRF3 MFAP3 NCOA6 NEK6 NR3C1 NUMBL PICK1 PPARG PRKD2 PRMT1 RXRA THRA UBE2I VDR WDR6 XDH	5 interacting genes: BRCA1 CDC42EP4 G2E3 GRIP1 PTPN3
Entrez ID		23426	11180
HPRD ID		19086	06912
Ensembl ID		ENSG00000155974	ENSG00000178252
Uniprot IDs		Q9Y3R0	A0A087X295 B3KRR8 B4E256 E9PDU5 Q9H9M3 Q9NNW5
PDB IDs		2JIL
Enriched GO Terms of Interacting Partners?
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