GRIP1 and CSPG4

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid, in vivo)

		GRIP1	CSPG4
Description		glutamate receptor interacting protein 1	chondroitin sulfate proteoglycan 4
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Postsynaptic Density Dendrite Cytoplasmic Vesicle Neuron Projection Perikaryon Membrane Raft Postsynaptic Membrane Glutamatergic Synapse	Ruffle Extracellular Region Nucleoplasm Golgi Lumen Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Cell Surface Apical Plasma Membrane Lamellipodium Membrane Lysosomal Lumen Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Protein Binding Beta-catenin Binding Protein C-terminus Binding Signaling Receptor Complex Adaptor Activity Glucocorticoid Receptor Binding	Coreceptor Activity Protein Kinase Binding
	Biological Process	Dendrite Development Intracellular Signal Transduction Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Vesicle-mediated Transport In Synapse Positive Regulation Of Neuron Projection Arborization	Activation Of MAPK Activity Angiogenesis Substrate-dependent Cell Migration Cell Population Proliferation Glial Cell Migration Chondroitin Sulfate Biosynthetic Process Chondroitin Sulfate Catabolic Process Dermatan Sulfate Biosynthetic Process Intracellular Signal Transduction Platelet-derived Growth Factor Receptor Signaling Pathway Tissue Remodeling Positive Regulation Of Peptidyl-tyrosine Phosphorylation Ruffle Assembly
Pathways		Trafficking of GluR2-containing AMPA receptors	A tetrasaccharide linker sequence is required for GAG synthesis Chondroitin sulfate biosynthesis Dermatan sulfate biosynthesis CS/DS degradation Defective B4GALT7 causes EDS, progeroid type Defective B3GAT3 causes JDSSDHD Defective CHST3 causes SEDCJD Defective CHST14 causes EDS, musculocontractural type Defective CHSY1 causes TPBS Defective B3GALT6 causes EDSP2 and SEMDJL1
Drugs
Diseases
GWAS		Basophil percentage of granulocytes ( 27863252) Basophil percentage of white cells ( 27863252) Post bronchodilator FEV1/FVC ratio ( 26634245)	Estimated glomerular filtration rate ( 31015462) Intraocular pressure ( 29617998) Simvastatin-induced myopathy ( 31220337)
Interacting Genes		42 interacting genes: AGAP2 AR CARM1 CSPG4 DEPDC1B DZIP3 EEPD1 EFNA5 EFNB1 EFNB2 EP300 ESR1 FGF12 FLII GPR37 GRIA1 GRIA3 GRIA4 GRIK1 GRIK2 GRIPAP1 GRM2 GRM3 GRM7 H3C1 HUS1 IRF3 MFAP3 NCOA6 NEK6 NR3C1 NUMBL PICK1 PPARG PRKD2 PRMT1 RXRA THRA UBE2I VDR WDR6 XDH	9 interacting genes: ATF7IP BCAR1 C1QA CDC42 GRIP1 GRIP2 MPDZ PTK2 TNK2
Entrez ID		23426	1464
HPRD ID		19086	03105
Ensembl ID		ENSG00000155974	ENSG00000173546
Uniprot IDs		Q9Y3R0	Q6UVK1
PDB IDs		2JIL
Enriched GO Terms of Interacting Partners?
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