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ZDHHC17 and GATA1
Data Source:
BioGRID
(two hybrid)
ZDHHC17
GATA1
Description
zinc finger DHHC-type palmitoyltransferase 17
GATA binding protein 1
Image
GO Annotations
Cellular Component
Golgi Membrane
Golgi Apparatus
Integral Component Of Membrane
Aggresome
Cytoplasmic Vesicle Membrane
Golgi-associated Vesicle Membrane
Presynaptic Membrane
Cell Projection
Intracellular Membrane-bounded Organelle
Chromatin
Nucleus
Nucleoplasm
Transcription Regulator Complex
Transcription Repressor Complex
Protein-DNA Complex
Molecular Function
Signaling Receptor Binding
Protein Binding
Magnesium Ion Transmembrane Transporter Activity
Palmitoyltransferase Activity
Protein-cysteine S-palmitoyltransferase Activity
Identical Protein Binding
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
RNA Polymerase II Transcription Factor Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
P53 Binding
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Zinc Ion Binding
Chromatin DNA Binding
Sequence-specific DNA Binding
C2H2 Zinc Finger Domain Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Axonogenesis
Protein Phosphopantetheinylation
Peptidyl-L-cysteine S-palmitoylation
Protein Palmitoylation
Lipoprotein Transport
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Regulation Of Neurotrophin TRK Receptor Signaling Pathway
Regulation Of ERK1 And ERK2 Cascade
Magnesium Ion Transmembrane Transport
Negative Regulation Of Transcription By RNA Polymerase II
In Utero Embryonic Development
Regulation Of Transcription By RNA Polymerase II
Cell-cell Signaling
Blood Coagulation
Negative Regulation Of Cell Population Proliferation
Male Gonad Development
Regulation Of Glycoprotein Biosynthetic Process
Regulation Of Definitive Erythrocyte Differentiation
Regulation Of Primitive Erythrocyte Differentiation
Erythrocyte Differentiation
Megakaryocyte Differentiation
Platelet Formation
Basophil Differentiation
Eosinophil Differentiation
Negative Regulation Of Bone Mineralization
Positive Regulation Of Osteoblast Proliferation
Embryonic Hemopoiesis
Eosinophil Fate Commitment
Negative Regulation Of Apoptotic Process
Cell Fate Commitment
Positive Regulation Of Erythrocyte Differentiation
Regulation Of Megakaryocyte Differentiation
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Erythrocyte Development
Homeostasis Of Number Of Cells Within A Tissue
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Platelet Aggregation
Transcriptional Activation By Promoter-enhancer Looping
Dendritic Cell Differentiation
Cellular Response To Thyroid Hormone Stimulus
Regulation Of Hematopoietic Stem Cell Differentiation
Negative Regulation Of Transcription Regulatory Region DNA Binding
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
Thrombocytopenia (THC); Familial platelet disorder with associated myeloid malignancy (FPDMM)
Congenital dyserythropoietic anemias (CDAs)
GWAS
Mean arterial pressure x educational attainment (some college) interaction (2df) (
32372009
)
Metabolite levels (
23823483
)
Visceral fat (
30942860
)
Eosinophil counts (
32888494
)
Eosinophil percentage of white cells (
32888494
)
Interacting Genes
192 interacting genes:
-
ABCG4
ACTR1B
ADD1
AHDC1
AIDA
AK3
ALKBH3
ANKRD50
ANXA11
APBB1IP
ARFGAP3
ASF1A
ASIC4
BCAS3
BEX2
BTF3
C1orf216
C20orf141
CBS
CCDC120
CCDC7
CCNE2
CDSN
CENPBD1P1
CHMP1A
CIB1
CLRN3
CNDP2
CNKSR1
COG3
CSTA
CTCFL
CTHRC1
DALRD3
DELE1
DIXDC1
DLG4
DLK1
DR1
DTX3
E2F8
EDRF1
EEF1G
ERCC6L
EVL
EXOSC9
EYA3
FAM207A
FAM9A
FBH1
FOXD4L6
FTL
FUT2
FUT9
GABPB1
GABPB2
GATA1
GOLPH3L
GPR135
GRB10
GUSBP3
H2AP
H2BC9
H3C10
HBG1
HECTD3
HLA-A
HLA-DRB1
HMBS
HOXA3
HS1BP3
HTT
IFT20
IFT57
INPP5D
JMJD7-PLA2G4B
KHDC4
KIAA0408
KNSTRN
KRAS
KRT17
KRT8P12
KRTAP11-1
KRTAP9-2
LCA5L
LGALS9C
LIN28A
LMAN2L
LNCRI
LRRC45
LY6G6C
MANF
MAP3K19
MIIP
MLH3
MRFAP1
MRFAP1L1
MSANTD3
MSRB2
MYBPHL
MYOZ2
NCBP1
NEBL
NFATC2IP
NFYC
NIFK
NPFF
ODF2
OFCC1
OTUD7B
OTX2
PABIR3
PBRM1
PDZK1IP1
PHF5A
PLEKHB1
PPP1R21
PPTC7
PRMT5
PTMA
QRICH1
RAB39B
RAD51
RANGRF
RAP1B
RBM5
RCAN3
RIC8A
RNF20
RNF38
RSBN1L
RUBCNL
SCNM1
SEMA4G
SF3A3
SHOX2
SKA3
SLC1A3
SLC25A31
SLC9A9
SMARCB1
SNAP25
SOX14
SP2
SPRED2
SPRY3
SPRY4
SREBF2
SRSF4
STK25
STN1
SUMF2
SYT1
TEAD1
THAP7
TIGD1
TMC6
TMCC1
TMEM115
TMEM186
TMTC1
TNFAIP1
TNFSF10
TOX
TPGS2
TTC23
TTLL7
TUT7
TXNDC12
TXNDC15
UBAC1
UBE2K
USP18
USP32
VN1R10P
VSX2
WAC
WDR20
YIF1A
YTHDF3
ZCCHC17
ZFC3H1
ZFP2
ZFP36
ZFYVE19
ZNF333
ZNF341
ZNF597
ZNF624
ZNF667-AS1
ZSCAN9
85 interacting genes:
AKT1
ARID1A
ARMC7
ATP6V0D1
BCL6
CASP3
CCDC24
CEBPE
CHRD
CREBBP
DGCR6L
DNMT3L
FANCG
FANCL
FBF1
FHL3
FLI1
FRS3
GLRX3
GOLGA2
GRAP2
HDAC3
HDAC4
HDAC5
HEMGN
HEXIM2
HEY1
HOXA1
HSPA4
KANK2
KRTAP10-5
KRTAP3-2
KRTAP4-11
KRTAP4-5
KRTAP9-2
LMO2
LZTS2
MAPK1
MAPK3
MAPK6
MDFI
MED1
MGAT5B
MKRN3
PITX1
PLSCR4
PML
PNMA1
PPP1R16B
PRKAA1
PRKAB2
PSMF1
RADIL
RAI1
RBPMS
RIN3
SMARCA4
SMARCB1
SMARCC1
SMARCC2
SMARCD1
SMARCE1
SP1
SPI1
SPIB
SRA1
STAT3
TAF7
TAL1
TAX1BP3
TEKT4
TLE5
TNS2
TRAF1
TRIM25
TRIM29
TRIP6
USP7
ZBTB16
ZBTB22
ZDHHC17
ZFPM1
ZFPM2
ZNF521
ZZZ3
Entrez ID
23390
2623
HPRD ID
09697
02372
Ensembl ID
ENSG00000186908
ENSG00000102145
Uniprot IDs
Q8IUH5
P15976
PDB IDs
3EU9
5W7I
5W7J
6G0Q
Enriched GO Terms of Interacting Partners
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