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ZDHHC17 and RAB39B
Data Source:
BioGRID
(two hybrid, affinity chromatography technology)
ZDHHC17
RAB39B
Description
zinc finger DHHC-type palmitoyltransferase 17
RAB39B, member RAS oncogene family
Image
GO Annotations
Cellular Component
Golgi Membrane
Golgi Apparatus
Integral Component Of Membrane
Aggresome
Cytoplasmic Vesicle Membrane
Golgi-associated Vesicle Membrane
Presynaptic Membrane
Cell Projection
Intracellular Membrane-bounded Organelle
Golgi Membrane
Golgi Apparatus
Plasma Membrane
Cytoplasmic Vesicle Membrane
Vesicle
Neuron Projection
Molecular Function
Signaling Receptor Binding
Protein Binding
Magnesium Ion Transmembrane Transporter Activity
Palmitoyltransferase Activity
Protein-cysteine S-palmitoyltransferase Activity
Identical Protein Binding
GTPase Activity
Protein Binding
GTP Binding
Myosin V Binding
Biological Process
Axonogenesis
Protein Phosphopantetheinylation
Peptidyl-L-cysteine S-palmitoylation
Protein Palmitoylation
Lipoprotein Transport
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Regulation Of Neurotrophin TRK Receptor Signaling Pathway
Regulation Of ERK1 And ERK2 Cascade
Magnesium Ion Transmembrane Transport
Autophagy
Regulation Of Autophagy
Protein Transport
Vesicle-mediated Transport
Rab Protein Signal Transduction
Synapse Organization
Pathways
RAB geranylgeranylation
RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
Syndromic X-linked mental retardation with epilepsy or seizures, including: West syndrome (WS); Partington syndrome (PRTS); Proud syndrome (ACCAG); XMR and epilepsy (XMRE); MRXHF1; XMR OPHN1-related (MRXSO) ; XELBD; XMR, Christianson type (MRXSC); Creatine deficiency syndrome (XL-CDS); Renpenning syndrome (RENS1); Epilepsy and mental retardation limited to females (EFMR); Periventricular nodular heterotopia (PVNH); Hydrocephalus (XLH); XMR, JARID1C related (MRXSJ); Boerjeson-Forssman syndrome (BFLS); CK syndrome (CKS)
GWAS
Mean arterial pressure x educational attainment (some college) interaction (2df) (
32372009
)
Metabolite levels (
23823483
)
Visceral fat (
30942860
)
Interacting Genes
192 interacting genes:
-
ABCG4
ACTR1B
ADD1
AHDC1
AIDA
AK3
ALKBH3
ANKRD50
ANXA11
APBB1IP
ARFGAP3
ASF1A
ASIC4
BCAS3
BEX2
BTF3
C1orf216
C20orf141
CBS
CCDC120
CCDC7
CCNE2
CDSN
CENPBD1P1
CHMP1A
CIB1
CLRN3
CNDP2
CNKSR1
COG3
CSTA
CTCFL
CTHRC1
DALRD3
DELE1
DIXDC1
DLG4
DLK1
DR1
DTX3
E2F8
EDRF1
EEF1G
ERCC6L
EVL
EXOSC9
EYA3
FAM207A
FAM9A
FBH1
FOXD4L6
FTL
FUT2
FUT9
GABPB1
GABPB2
GATA1
GOLPH3L
GPR135
GRB10
GUSBP3
H2AP
H2BC9
H3C10
HBG1
HECTD3
HLA-A
HLA-DRB1
HMBS
HOXA3
HS1BP3
HTT
IFT20
IFT57
INPP5D
JMJD7-PLA2G4B
KHDC4
KIAA0408
KNSTRN
KRAS
KRT17
KRT8P12
KRTAP11-1
KRTAP9-2
LCA5L
LGALS9C
LIN28A
LMAN2L
LNCRI
LRRC45
LY6G6C
MANF
MAP3K19
MIIP
MLH3
MRFAP1
MRFAP1L1
MSANTD3
MSRB2
MYBPHL
MYOZ2
NCBP1
NEBL
NFATC2IP
NFYC
NIFK
NPFF
ODF2
OFCC1
OTUD7B
OTX2
PABIR3
PBRM1
PDZK1IP1
PHF5A
PLEKHB1
PPP1R21
PPTC7
PRMT5
PTMA
QRICH1
RAB39B
RAD51
RANGRF
RAP1B
RBM5
RCAN3
RIC8A
RNF20
RNF38
RSBN1L
RUBCNL
SCNM1
SEMA4G
SF3A3
SHOX2
SKA3
SLC1A3
SLC25A31
SLC9A9
SMARCB1
SNAP25
SOX14
SP2
SPRED2
SPRY3
SPRY4
SREBF2
SRSF4
STK25
STN1
SUMF2
SYT1
TEAD1
THAP7
TIGD1
TMC6
TMCC1
TMEM115
TMEM186
TMTC1
TNFAIP1
TNFSF10
TOX
TPGS2
TTC23
TTLL7
TUT7
TXNDC12
TXNDC15
UBAC1
UBE2K
USP18
USP32
VN1R10P
VSX2
WAC
WDR20
YIF1A
YTHDF3
ZCCHC17
ZFC3H1
ZFP2
ZFP36
ZFYVE19
ZNF333
ZNF341
ZNF597
ZNF624
ZNF667-AS1
ZSCAN9
6 interacting genes:
GOLGA2
RAB3GAP1
RUFY1
SGSM3
VPS26C
ZDHHC17
Entrez ID
23390
116442
HPRD ID
09697
06703
Ensembl ID
ENSG00000186908
ENSG00000155961
Uniprot IDs
Q8IUH5
Q96DA2
PDB IDs
3EU9
5W7I
5W7J
6S5F
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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