DOCK9 and ATG12

Data Source:
BioGRID (two hybrid)

		DOCK9	ATG12
Description		dedicator of cytokinesis 9	autophagy related 12
Image
GO Annotations	Cellular Component	Cytosol Endomembrane System Membrane	Autophagosome Cytosol Phagocytic Vesicle Membrane Phagophore Assembly Site Membrane Atg12-Atg5-Atg16 Complex
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Cadherin Binding	Protein Binding
	Biological Process	Small GTPase Mediated Signal Transduction Blood Coagulation Biological_process Positive Regulation Of GTPase Activity	Autophagosome Assembly Autophagy Of Mitochondrion C-terminal Protein Lipidation Viral Process Macroautophagy Autophagy Of Nucleus
Pathways		Factors involved in megakaryocyte development and platelet production	Macroautophagy Macroautophagy PINK1-PRKN Mediated Mitophagy Receptor Mediated Mitophagy Negative regulators of DDX58/IFIH1 signaling
Drugs
Diseases
GWAS		Asthma (childhood onset) ( 31036433) Blood urea nitrogen levels ( 31152163 29403010) Corneal astigmatism ( 30306274) FEV1 ( 30804560) Heel bone mineral density ( 30598549 28869591) Lung function (FEV1/FVC) ( 30804560) Nonsyndromic cleft palate ( 31609978) Platelet distribution width ( 32888494) QRS interval (sulfonylurea treatment interaction) ( 27958378) Refractive error ( 32231278) White blood cell count ( 32888494)
Interacting Genes		11 interacting genes: ATG12 CDC42 CLK1 FHL1 LNX1 MYOT NEDD9 NUCKS1 PPP2R5E SNAPIN TAF1	15 interacting genes: APP ATG10 ATG3 ATG5 ATG7 CRX DOCK9 IER2 KRTAP4-12 MDFI MEOX2 PLSCR1 PTK2 SERTAD1 SERTAD2
Entrez ID		23348	9140
HPRD ID		09542	08496
Ensembl ID		ENSG00000088387	ENSG00000145782
Uniprot IDs		A0A0A0MT38 A6H8Z6 B3KXE2 B7Z2G6 B9EG73 Q9BZ29	O94817
PDB IDs		1WG7 2WM9 2WMN 2WMO	4GDK 4GDL 4NAW
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?