ATG12 and ATG3

Data Source:
HPRD (in vivo)

		ATG12	ATG3
Description		autophagy related 12	autophagy related 3
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GO Annotations	Cellular Component	Autophagosome Cytosol Phagocytic Vesicle Membrane Phagophore Assembly Site Membrane Atg12-Atg5-Atg16 Complex	Cytoplasmic Ubiquitin Ligase Complex Cytosol
	Molecular Function	Protein Binding	Protein Binding Atg8 Ligase Activity Atg12 Transferase Activity Ubiquitin-like Protein Transferase Activity Enzyme Binding
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion C-terminal Protein Lipidation Viral Process Macroautophagy Autophagy Of Nucleus	Autophagosome Assembly Autophagy Of Mitochondrion Cellular Protein Modification Process Protein Targeting To Membrane Macroautophagy Protein Ubiquitination Protein Phosphopantetheinylation Mitochondrial Fragmentation Involved In Apoptotic Process Autophagy Of Nucleus Negative Regulation Of Phagocytosis Regulation Of Cilium Assembly
Pathways		Macroautophagy Macroautophagy PINK1-PRKN Mediated Mitophagy Receptor Mediated Mitophagy Negative regulators of DDX58/IFIH1 signaling	Macroautophagy
Drugs
Diseases
GWAS			Asthma (childhood onset) ( 23829686)
Interacting Genes		15 interacting genes: APP ATG10 ATG3 ATG5 ATG7 CRX DOCK9 IER2 KRTAP4-12 MDFI MEOX2 PLSCR1 PTK2 SERTAD1 SERTAD2	7 interacting genes: ATG12 ATG7 BECN1 GABARAP GABARAPL2 MAP1LC3B MOB2
Entrez ID		9140	64422
HPRD ID		08496	10654
Ensembl ID		ENSG00000145782	ENSG00000144848
Uniprot IDs		O94817	Q9NT62
PDB IDs		4GDK 4GDL 4NAW	4NAW
Enriched GO Terms of Interacting Partners?
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