MAN2B2 and CPLX4

Data Source:
BioGRID (two hybrid)

		MAN2B2	CPLX4
Description		mannosidase alpha class 2B member 2	complexin 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosome Vacuolar Membrane Lysosomal Lumen Extracellular Exosome	Plasma Membrane SNARE Complex Terminal Bouton
	Molecular Function	Alpha-mannosidase Activity Protein Binding Carbohydrate Binding Metal Ion Binding	SNARE Binding Protein Binding Syntaxin Binding
	Biological Process	Mannose Metabolic Process Oligosaccharide Catabolic Process	Visual Perception Synaptic Vesicle Exocytosis Regulation Of Neurotransmitter Secretion Response To Stimulus
Pathways		Lysosomal oligosaccharide catabolism
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Metabolite levels ( 23823483)	Cardiac troponin-I levels ( 31014085) Chronotype ( 27494321) Macular thickness ( 30535121) Morning vs. evening chronotype ( 27494321)
Interacting Genes		9 interacting genes: APPBP2 CISD2 CPLX4 CREB3L1 FKBP7 GPX8 KCNK5 KRTAP3-2 LIME1	92 interacting genes: ADIPOQ AGTRAP AIG1 AOC3 APOD AQP1 AQP9 ASGR1 ATP6V0C BNIP2 C14orf180 C1GALT1 C3orf52 C5 CACNG1 CCL4L2 CD81 CDIPT CDS2 CLDND2 CLEC4G CLN6 CMTM5 CNIH1 CTSA CTXN3 CYB5B CYBC1 CYP4F2 DEFB127 EMD GAD2 GIMAP1 GRM2 HACD1 HHATL HMOX1 INSIG2 LPAR3 MAL MALL MAN2B2 MGAM NINJ2 NRM ORMDL1 PGAP2 PLN PLP2 PLPP4 PNLIPRP1 PTPN9 RTP2 SEC22B SELENOK SFTPC SLC30A2 SLC30A8 SLC35A1 SLC35A4 SLC35B4 SLC38A7 SLC39A9 SMCO4 STX3 STX8 SYNJ2BP TF TMEM120B TMEM14A TMEM14B TMEM19 TMEM201 TMEM203 TMEM218 TMEM229B TMEM243 TMEM254 TMEM267 TMEM60 TMEM79 TMEM86A TMEM97 TRAF3IP3 TSPO2 UBIAD1 VAMP4 VAMP5 VKORC1 WFDC2 YIPF6 ZFPL1
Entrez ID		23324	339302
HPRD ID		14355	13091
Ensembl ID		ENSG00000013288	ENSG00000166569
Uniprot IDs		B7Z754 E9PCD7 Q9Y2E5	Q7Z7G2
PDB IDs
Enriched GO Terms of Interacting Partners?
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