MGRN1 and UBE2J2

Data Source:
BioGRID (two hybrid)

		MGRN1	UBE2J2
Description		mahogunin ring finger 1	ubiquitin conjugating enzyme E2 J2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Early Endosome Endoplasmic Reticulum Cytosol Plasma Membrane Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome	Ubiquitin Ligase Complex Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Protein Monoubiquitination Endosome To Lysosome Transport Protein Ubiquitination Negative Regulation Of CAMP-mediated Signaling Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Smoothened Signaling Pathway	Protein Polyubiquitination Response To Unfolded Protein Protein Ubiquitination Ubiquitin-dependent ERAD Pathway Positive Regulation Of Protein Targeting To Mitochondrion
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	E3 ubiquitin ligases ubiquitinate target proteins Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		HDL cholesterol levels ( 32203549) Hemoglobin ( 32888494) Milk allergy (maternal genetic effects) ( 29489655) Triglyceride levels ( 32154731)	Inflammatory bowel disease ( 28067908) Systemic lupus erythematosus ( 28714469) Ulcerative colitis ( 28067908)
Interacting Genes		13 interacting genes: AMFR TRIM74 TSG101 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2G2 UBE2I UBE2J2 UBE2T UBE2W	21 interacting genes: AQP6 ATP13A2 ELOVL7 FBXO7 HECW1 HERC4 ITCH MDM2 MGRN1 NEDD4L PRKN RBP1 RNF10 TMEM14B TRIM25 TRIM59 UBA1 UBC UBE2G2 WWP2 XIAP
Entrez ID		23295	118424
HPRD ID		07397	15600
Ensembl ID		ENSG00000102858	ENSG00000160087
Uniprot IDs		O60291	A0A024R075 A6NGS0 Q8N2K1
PDB IDs			2F4W
Enriched GO Terms of Interacting Partners?
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