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UBE2J2 and UBE2G2
Data Source:
HPRD
(in vivo)
UBE2J2
UBE2G2
Description
ubiquitin conjugating enzyme E2 J2
ubiquitin conjugating enzyme E2 G2
Image
GO Annotations
Cellular Component
Ubiquitin Ligase Complex
Nucleus
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Integral Component Of Membrane
Endoplasmic Reticulum
Lipid Droplet
Cytosol
Molecular Function
Protein Binding
ATP Binding
Ubiquitin Protein Ligase Binding
Ubiquitin Conjugating Enzyme Activity
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Identical Protein Binding
Ubiquitin Conjugating Enzyme Activity
Biological Process
Protein Polyubiquitination
Response To Unfolded Protein
Protein Ubiquitination
Ubiquitin-dependent ERAD Pathway
Positive Regulation Of Protein Targeting To Mitochondrion
Protein Polyubiquitination
Ubiquitin-dependent Protein Catabolic Process
Protein Ubiquitination
Ubiquitin-dependent ERAD Pathway
Cellular Response To Interferon-beta
Cellular Protein Catabolic Process
Protein K48-linked Ubiquitination
Negative Regulation Of Retrograde Protein Transport, ER To Cytosol
Pathways
E3 ubiquitin ligases ubiquitinate target proteins
Antigen processing: Ubiquitination & Proteasome degradation
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Inflammatory bowel disease (
28067908
)
Systemic lupus erythematosus (
28714469
)
Ulcerative colitis (
28067908
)
Interacting Genes
21 interacting genes:
AQP6
ATP13A2
ELOVL7
FBXO7
HECW1
HERC4
ITCH
MDM2
MGRN1
NEDD4L
PRKN
RBP1
RNF10
TMEM14B
TRIM25
TRIM59
UBA1
UBC
UBE2G2
WWP2
XIAP
39 interacting genes:
AMFR
ARL14
AUP1
BIRC8
CBL
CNNM3
CPOX
CUL9
ECPAS
FARP2
HBS1L
KDM2A
MDM2
MGRN1
MLLT6
MUL1
NDUFS4
POLR3F
PRKN
RBX1
RC3H1
RC3H2
RFFL
RNF111
RNF146
RNF157
RNF168
RNF26
RNF5
TMEM45B
TRIM3
TRIM43
UBA1
UBA6
UBC
UBE2J2
UBE3A
VAMP8
ZNRF4
Entrez ID
118424
7327
HPRD ID
15600
04387
Ensembl ID
ENSG00000160087
ENSG00000184787
Uniprot IDs
A0A024R075
A6NGS0
Q8N2K1
P60604
PDB IDs
2F4W
2CYX
2KLY
2LXP
3H8K
4LAD
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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