MGRN1 and UBE2T

Data Source:
BioGRID (two hybrid)

		MGRN1	UBE2T
Description		mahogunin ring finger 1	ubiquitin conjugating enzyme E2 T
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Early Endosome Endoplasmic Reticulum Cytosol Plasma Membrane Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome	Nucleus Nucleoplasm Nucleolus
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Chromatin Binding Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Protein Monoubiquitination Endosome To Lysosome Transport Protein Ubiquitination Negative Regulation Of CAMP-mediated Signaling Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Smoothened Signaling Pathway	Protein Polyubiquitination DNA Repair Protein Monoubiquitination Cellular Response To DNA Damage Stimulus Protein Ubiquitination Protein K29-linked Ubiquitination Interstrand Cross-link Repair Protein K27-linked Ubiquitination Protein Autoubiquitination Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination Protein K6-linked Ubiquitination
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Fanconi Anemia Pathway Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Drugs
Diseases
GWAS		HDL cholesterol levels ( 32203549) Hemoglobin ( 32888494) Milk allergy (maternal genetic effects) ( 29489655) Triglyceride levels ( 32154731)	Breast cancer ( 23535733) Celiac disease ( 23936387)
Interacting Genes		13 interacting genes: AMFR TRIM74 TSG101 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2G2 UBE2I UBE2J2 UBE2T UBE2W	22 interacting genes: AMFR ARIH2 BRCA1 CDK2 CHEK1 FANCD2 FANCL LNX2 MARCHF5 MGRN1 PCGF2 PRKCG PRKN RNF128 RNF144B RNF31 RNF4 ROCK1 RPS6KA1 TRIM27 UBA1 UBA6
Entrez ID		23295	29089
HPRD ID		07397	13704
Ensembl ID		ENSG00000102858	ENSG00000077152
Uniprot IDs		O60291	A0A024R9A9 Q9NPD8
PDB IDs			1YH2 4CCG 5NGZ 5OJJ 6R75
Enriched GO Terms of Interacting Partners?
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