SYT11 and SGTB

Data Source:
BioGRID (two hybrid)

		SYT11	SGTB
Description		synaptotagmin 11	small glutamine rich tetratricopeptide repeat co-chaperone beta
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Phagocytic Cup Lysosome Lysosomal Membrane Trans-Golgi Network Plasma Membrane Synaptic Vesicle Postsynaptic Density Axon Dendrite Clathrin-coated Vesicle Membrane Vesicle Early Phagosome Neuron Projection Terminal Bouton Dendritic Spine Perikaryon Synapse Phagocytic Vesicle Perinuclear Region Of Cytoplasm Presynaptic Active Zone Membrane Recycling Endosome Recycling Endosome Membrane Excitatory Synapse Inhibitory Synapse Exocytic Vesicle Schaffer Collateral - CA1 Synapse Presynapse Integral Component Of Presynaptic Active Zone Membrane	Membrane TRC Complex
	Molecular Function	SNARE Binding Phosphatidylserine Binding Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Clathrin Binding Translation Initiation Factor Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Beta-tubulin Binding	Protein Binding Molecular Adaptor Activity
	Biological Process	Plasma Membrane Repair Negative Regulation Of Cytokine Production Vesicle Fusion Autophagy Learning Memory Regulation Of Dopamine Secretion Vesicle-mediated Transport Calcium-ion Regulated Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Negative Regulation Of Interleukin-6 Production Negative Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Dopamine Secretion Negative Regulation Of Endocytosis Negative Regulation Of Neurotransmitter Secretion Negative Regulation Of Phagocytosis Establishment Of Vesicle Localization Cellular Response To Calcium Ion Negative Regulation Of Clathrin-dependent Endocytosis Negative Regulation Of Synaptic Vesicle Endocytosis Regulation Of Defense Response To Bacterium Negative Regulation Of Microglial Cell Activation Negative Regulation Of Membrane Invagination Regulation Of Phagosome Maturation Positive Regulation Of Protein Localization To Phagocytic Vesicle Negative Regulation Of Clathrin-coated Pit Assembly Calcium Ion Regulated Lysosome Exocytosis	Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Ubiquitin-dependent ERAD Pathway Positive Regulation Of Chaperone-mediated Protein Folding
Pathways		Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 28892062) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Parkinson's disease ( 21292315 25064009) Serum cancer antigen 15.3 levels ( 31666285) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		6 interacting genes: APPBP2 GPR35 PRKN SGTA SGTB SYNCRIP	116 interacting genes: ABCG4 ADAT2 ADIPOQ AGR2 AGR3 ASPH BTC C1QA C1QL4 C1QTNF5 C1QTNF6 C5orf46 CALR CCL3L3 CD200R1 CD3D CD68 CD79B CD99L2 CDH15 CDSN CMPK1 COL10A1 COL1A2 COLQ COMP CREB3L3 CSH1 CSH2 CTAG1A CTAG1B CYB5R1 DEFA6 DEXI DMKN ECM1 EFEMP2 EMCN ERP29 ETNK1 EVA1A FBN1 FGF21 FZD7 GALNT11 GGH GIP GPX7 GYPA HSP90B1 HSPA13 IL6R IL6ST ITPRIP ITPRIPL1 KCNE5 KRT1 LAMP3 LAT LCN2 LHB LMO2 MYDGF NAXD NME3 OSMR PAGE3 PDIA6 PGRMC1 PODXL PPIB PPIC PRAP1 PRB1 PRB3 PRB4 PRR4 PSORS1C2 RAI2 RCN1 RNASE10 RNF144A RNF144B RNF170 SDC4 SDF2L1 SELENOM SERPINE1 SERPINF1 SERPINI2 SGCA SGTA SHISA5 SIL1 SLPI SOD3 SPINK4 SPP1 SRGN SYT11 SYT4 TFF1 TMEM108 TMEM123 TMPO TMUB1 TNFRSF19 TNFSF13 TXNDC12 UBL4A UPK3A VEGFC VWC2 WFDC12 ZG16 ZG16B
Entrez ID		23208	54557
HPRD ID		12289	18049
Ensembl ID		ENSG00000132718	ENSG00000197860
Uniprot IDs		Q9BT88	Q96EQ0
PDB IDs
Enriched GO Terms of Interacting Partners?
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