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FAM168A and DTX2
Data Source:
BioGRID
(two hybrid, two hybrid)
FAM168A
DTX2
Description
family with sequence similarity 168 member A
deltex E3 ubiquitin ligase 2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Nuclear Membrane
Molecular Function
Protein Binding
Protein Binding
Zinc Ion Binding
Ubiquitin Protein Ligase Activity
Biological Process
Positive Regulation Of Base-excision Repair
Notch Signaling Pathway
Protein Ubiquitination
Pathways
Activated NOTCH1 Transmits Signal to the Nucleus
Activated NOTCH1 Transmits Signal to the Nucleus
Drugs
Diseases
GWAS
Apolipoprotein A1 levels (
32203549
)
Blood protein levels (
28240269
)
Diastolic blood pressure (
30224653
)
Heel bone mineral density (
30598549
)
Lung function (FEV1/FVC) (
30061609
)
Platelet count (
32888494
)
Pulmonary function (smoking interaction) (
23284291
)
Refractive error (
32231278
)
Waist-hip ratio (
28552196
)
Interacting Genes
75 interacting genes:
ALKBH4
ATXN1
ATXN1L
BOLL
C10orf55
C1orf94
CALCOCO2
CAMK2A
DAB1
DAZAP2
DCUN1D1
DTX2
EPN2
EPN3
FAM168B
FBXW5
HGS
HIP1
HR
KLHL42
KRTAP19-1
KRTAP19-5
KRTAP19-7
KRTAP3-1
KRTAP3-3
KRTAP6-2
KRTAP7-1
KRTAP8-1
LASP1
MEIS2
NAF1
NFYC
OTUB2
OTULIN
PATZ1
PEF1
PITX1
PLEKHB2
PROP1
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
PSORS1C1
R3HDM2
RBFOX1
RBPMS
RBPMS2
RHOXF2
RNF216
RPS27A
SECISBP2
SF1
SMAP2
SNRPC
SS18L1
TAX1BP1
TFAP2D
TFG
TIAL1
TNIP1
TNK1
TOLLIP
UBA52
UBAC1
UBASH3B
UBC
UBE2V1
UBQLN2
UBXN6
UBXN7
VPS37C
YOD1
YTHDF1
131 interacting genes:
ABHD11
ABHD16A
ALKBH4
ANAPC11
ANTKMT
ARID5A
ARMC7
ARNT2
BCL2L11
BICRAL
BOLA2-SMG1P6
C10orf55
C11orf1
C19orf54
C1orf94
C20orf85
C22orf39
CCDC57
CLPP
COA6
COQ8A
DAZAP2
DOK3
DTX1
DTX3
ECM1
ECSIT
EIF4ENIF1
EIF4G1
EYA2
FAM168A
FCRL4
FHL2
FHL5
FOXI1
FTO
GLYCTK
GOLGA2
HDC
HGS
HLX
HOXA1
HOXB2
HOXD12
HPCA
HPCAL1
HPCAL4
HSFY1
HSFY2
IKZF3
KANK2
KLC3
KLHDC7B
KRTAP11-1
KRTAP13-3
KRTAP15-1
KRTAP19-1
KRTAP19-6
KRTAP19-7
KRTAP26-1
KRTAP6-1
KRTAP7-1
KRTAP8-1
LASP1
LNX1
LRP2BP
MBD3L1
MDC1
MED19
MSS51
MVP
MXRA8
NCALD
NCS1
NHLRC4
NIF3L1
NME4
NOTCH1
OIP5
PARP1
PAX5
PLEKHF2
PLEKHG4
PLSCR1
POGZ
PPP1R32
PRR32
PRR34
PSMB4
QARS1
RBM11
RBPMS
RFX6
RHOXF2
RIMBP3
RUNX1
RUSC1
SEC22A
SEC23A
SEC23B
SEPSECS
SLC22A18AS
SOHLH1
SPAG8
SPG21
STX12
SUMO1
TBX15
TEKT5
TENT2
TMEM42
TRIB3
TRIM35
TRIM54
TRIP13
TRIP6
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBQLN4
USP54
VGLL3
VSNL1
ZNF34
ZNF503
ZNF620
ZNF641
ZNF764
ZNF774
ZNF85
Entrez ID
23201
113878
HPRD ID
13792
16841
Ensembl ID
ENSG00000054965
ENSG00000091073
Uniprot IDs
Q92567
Q86UW9
PDB IDs
6IR0
6Y22
6Y2X
6Y3J
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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