SAMD4A and TBC1D21

Data Source:
BioGRID (two hybrid)

		SAMD4A	TBC1D21
Description		sterile alpha motif domain containing 4A	TBC1 domain family member 21
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	P-body Fibrillar Center Cytosol Cell Junction Dendrite Synapse	Acrosomal Vesicle Cytoskeleton Extracellular Exosome
	Molecular Function	RNA Binding MRNA Binding Protein Binding Translation Repressor Activity	Actin Binding GTPase Activator Activity Protein Binding Small GTPase Binding
	Biological Process	Nuclear-transcribed MRNA Poly(A) Tail Shortening Negative Regulation Of Translation Regulation Of MRNA Stability Positive Regulation Of Translation	Intracellular Protein Transport Spermatogenesis Cell Differentiation Activation Of GTPase Activity Regulation Of Cilium Assembly
Pathways
Drugs
Diseases
GWAS		Cortical amyloid beta load ( 29860282) Creatine kinase levels ( 29403010) Hand grip strength ( 29313844) Height ( 31562340) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661) Plateletcrit ( 27863252) Pulse pressure ( 30224653) Subclinical trait of interstitial lung disease (basilar percentage of high attenuation areas on CT scan) ( 28521775) Tea consumption ( 31046077)	Coffee consumption (cups per day) ( 31837886) Estimated glomerular filtration rate ( 31152163) Exfoliation glaucoma or exfoliation syndrome ( 24938310) Feeling fed-up ( 29500382) Glucose homeostasis traits ( 25524916)
Interacting Genes		13 interacting genes: AKAP8L ANKRA2 BAG4 GOLGA2 HSF2BP MEOX2 MTUS2 NFKBID NUTM1 PRDM6 PRKAB2 TBC1D21 YWHAG	29 interacting genes: APP CCDC158 CFAP53 EVI5L GAS2 GFAP GTF2E1 KIF26A KRT15 KRT35 KRT37 KRT38 KRT40 LCN2 MEOX2 NR1D2 NUTM1 PDCD2 PMF1 PMF1-BGLAP RAB3IP REL RIBC1 SAMD4A SEPTIN2 SNX7 STMN3 TCF12 TIMM10
Entrez ID		23034	161514
HPRD ID		10209	15473
Ensembl ID		ENSG00000020577	ENSG00000167139
Uniprot IDs		G3V2R1 Q8WW19 Q9UPU9	Q8IYX1
PDB IDs
Enriched GO Terms of Interacting Partners?
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