SPEN and MSX2

  • Data Source:
  • HPRD (in vivo, in vitro)

SPEN

MSX2

Description spen family transcriptional repressor msh homeobox 2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653)
  • Blond vs. brown/black hair color ( 30531825)
  • Chin dimples ( 27182965)
  • Chronotype ( 30696823)
  • Depressive symptoms (SSRI exposure interaction) ( 25649181)
  • Metabolite levels ( 23823483)
  • Night sleep phenotypes ( 27126917)
  • Red vs. brown/black hair color ( 30531825)
  • Resistant hypertension ( 30237584)
  • Stroke ( 26089329)
Interacting Genes 22 interacting genes: ATXN1 CLK1 CTBP1 DLX5 HDAC1 HDAC2 MBD3 MSX2 MTA2 NCOR1 NCOR2 PPARD RARA RBBP4 RBPJ RIDA RUNX1 RUNX1T1 SERTAD1 SOX9 SRPK2 UBE2L6 54 interacting genes: ATXN1 CCDC102B CEBPA CLIC3 DLX2 DLX5 EPHB6 FBXW2 FOXH1 GATA2 GTF2F1 GTF2F2 HOXC9 LENG8 MAGED1 MAPK1 MAPK1IP1L MGAT5B MSX1 NAF1 NR3C1 PATZ1 PIAS2 PITX1 POLR3D POU1F1 POU2AF1 POU2F2 POU6F2 PPARG PRR13 RBPMS2 RHOXF2 ROR2 RUNX2 SMAP2 SOX5 SPEN TCF7L2 TENT5D TLE1 TLE2 TLE5 TLX3 TOLLIP TSSK3 VEZF1 XRCC5 XRCC6 YTHDF1 ZBTB17 ZC3H10 ZDHHC2 ZFHX3
Entrez ID 23013 4488
HPRD ID 10230 00421
Ensembl ID ENSG00000065526 ENSG00000120149
Uniprot IDs Q96T58 P35548
PDB IDs 1OW1 2RT5 4P6Q
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?