PTCD2 and USP49

Data Source:
BioGRID (two hybrid)

		PTCD2	USP49
Description		pentatricopeptide repeat domain 2	ubiquitin specific peptidase 49
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion	Nucleoplasm Cytoplasm
	Molecular Function	RNA Binding Protein Binding	Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Zinc Ion Binding Histone Binding
	Biological Process	Kidney Development Liver Development MRNA Processing Mitochondrion Organization Multicellular Organism Development Regulation Of Gene Expression Muscle Fiber Development Regulation Of MRNA Processing Ventricular Cardiac Muscle Tissue Morphogenesis	MRNA Splicing, Via Spliceosome Ubiquitin-dependent Protein Catabolic Process Protein Deubiquitination Protein Phosphopantetheinylation Histone H2B Conserved C-terminal Lysine Deubiquitination
Pathways			Ub-specific processing proteases
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Asthma ( 32296059) Asthma (childhood onset) ( 31036433) Glaucoma ( 31959993) Intraocular pressure ( 29617998 29785010 31959993 30054594) Pulse pressure ( 27841878) Refractive error ( 32231278)	Cutaneous psoriasis ( 26626624) Mean corpuscular hemoglobin ( 32888494 20139978) Mean corpuscular volume ( 23263863 32888494 20139978 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Neutrophil percentage of white cells ( 32888494) Platelet distribution width ( 32888494) Red blood cell count ( 32888494 20139978 27863252) Reticulocyte count ( 32888494) Skin aging (microtopography measurement) ( 28502801) Sleep duration (short sleep) ( 30846698)
Interacting Genes		4 interacting genes: MID1 MID2 TRIM32 USP49	12 interacting genes: FKBP5 H2BC21 MED17 MED18 MED8 NAMPT PTCD2 RBCK1 STING1 TP53 TRIM35 ZNF774
Entrez ID		79810	25862
HPRD ID		15193	10075
Ensembl ID		ENSG00000049883	ENSG00000164663
Uniprot IDs		A0A024RAM6 B3KPU6 B7Z8R2 F6S289 Q8WV60	Q70CQ1
PDB IDs
Enriched GO Terms of Interacting Partners?
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